Road trip from Columbia to Knoxville
All Category
Museums
Sights & Landmarks
Nightlife
Shopping
Fun & Games
Nature & Parks
Outdoor Activities
Show more (4+)
All Category
Museums
Sights & Landmarks
Nightlife
Shopping
Fun & Games
Nature & Parks
Outdoor Activities
Food & Drink
Spas & Wellness
Concerts & Shows
Reset
Show less
ITINERARY
5h 41m274 miles16 stops
1
Studio Cellar
2
West Main Artists Co-Op
3
Roper Mountain Science Center
Roper Mountain Science Center’s mission is to ignite the natural curiosity of all learners to explore and shape their world. Located just off of I-385 at Roper Mountain Road, Roper Mountain contains an array of state-of-the-art educational facilities on its 62-acre campus. Visitors experience the latest in STEM education through interactive exhibits and several hands-on activities. Families can attend numerous events throughout the year including Friday Starry Nights, Summer Adventure and Afterschool Explorations. Roper Mountain provides the opportunity to explore, imagine and grow as a learner of any age. Roper Mountain Science Center is only open to the public for select events throughout the yearFor more information, visit RoperMountain.org.
4
Greenville Zoo
5
Still Point Wellness Spa
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
6
French Broad River Brewery
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
7
Lexington Glassworks
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
8
Grove Arcade
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
9
Knoxville Botanical Garden
10
Muse Knoxville
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
11
Krutch Park
12
Peter Kern Library
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
13
The Mill and Mine
14
Knoxville National Cemetery
15
Cathedral of the Most Sacred Heart of Jesus
16
Radius Rooftop Lounge
Customize this Trip
OVERVIEW
1
Start:Studio Cellar
Columbia, South Carolina·
5.0
(9) review
912 Lady St The Vista, Columbia, SC 29201-3106
2
Start:West Main Artists Co-Op
Spartanburg, South Carolina·
5.0
(9) review
578 W Main St, Spartanburg, SC 29301-2162
3
Start:Roper Mountain Science Center
Greenville, South Carolina·
4.5
(90) review
Roper Mountain Science Center’s mission is to ignite the natural curiosity of all learners to explore and shape their world. Located just off of I-385 at Roper Mountain Road, Roper Mountain contains an array of state-of-the-art educational facilities on its 62-acre campus. Visitors experience the latest in STEM education through interactive exhibits and several hands-on activities. Families can attend numerous events throughout the year including Friday Starry Nights, Summer Adventure and Afterschool Explorations. Roper Mountain provides the opportunity to explore, imagine and grow as a learner of any age. Roper Mountain Science Center is only open to the public for select events throughout the yearFor more information, visit RoperMountain.org.
4
Start:Greenville Zoo
Greenville, South Carolina·
4.0
(996) review
150 Cleveland Park Dr, Greenville, SC 29601-3147
5
Start:Still Point Wellness Spa
Asheville, North Carolina·
5.0
(968) review
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
6
Start:French Broad River Brewery
Asheville, North Carolina·
4.0
(98) review
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
7
Start:Lexington Glassworks
Asheville, North Carolina·
4.5
(983) review
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
8
Start:Grove Arcade
Asheville, North Carolina·
4.0
(987) review
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
9
Start:Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
10
Start:Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
11
Start:Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
12
Start:Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
13
Start:The Mill and Mine
Knoxville, Tennessee·
5.0
(9) review
227 W Depot Ave, Knoxville, TN 37917-7521
14
Start:Knoxville National Cemetery
Knoxville, Tennessee·
5.0
(9) review
939 Tyson St, Knoxville, TN 37917-7143
15
Start:Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
16
Start:Radius Rooftop Lounge
Knoxville, Tennessee·
4.0
(9) review
Embassy Suites By Hilton 507 S Gay St, Knoxville, TN 37902
CHECKLIST
GPS device or app
Download Offline Map
Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
Camera or smartphone
Unlock Effortless Travel Planning
Create your dream trip in minutes by this prompt. Try now!
EXPLORE MORE
Discover Exciting Road Trip Inspirations
Columbia to Knoxville
274 miles
5h 41m
25 stops
MuseumsTraveler ResourcesSights & LandmarksNightlifeShopping
Columbia to Colorado Springs
1,587 miles
29h 16m
27 stops
MuseumsNightlifeShoppingOutdoor ActivitiesSights & Landmarks
Columbia to Baton Rouge
739 miles
13h 52m
26 stops
Nature & ParksFood & DrinkMuseumsNightlifeTours
Columbia to Concord
2,685 miles
47h 55m
40 stops
MuseumsSights & LandmarksNature & ParksShoppingNightlife
Columbia to Springfield
846 miles
16h 52m
28 stops
MuseumsNightlifeShoppingFun & GamesTours
Columbia to Ogden
2,071 miles
37h 22m
30 stops
MuseumsNightlifeShoppingOutdoor ActivitiesSights & Landmarks
EXPLORE OTHER
Check Out Different Road Trip Options
Brooklyn to Murfreesboro
894 miles
16h 55m
36 stops
ToursSights & LandmarksNature & ParksNightlifeMuseums
New York to Boston
213 miles
4h 38m
24 stops
Fun & GamesNightlifeSights & LandmarksOutdoor ActivitiesNature & Parks
Baltimore to Long Beach
2,650 miles
47h 29m
46 stops
Traveler ResourcesNature & ParksFun & GamesMuseumsSights & Landmarks
Huntsville to Waco
761 miles
14h 6m
23 stops
ShoppingTraveler ResourcesConcerts & ShowsOutdoor ActivitiesSights & Landmarks
Lexington to Spring Valley
1,944 miles
34h 6m
22 stops
Concerts & ShowsMuseumsOutdoor ActivitiesFun & GamesWater & Amusement Parks
Seattle to Muskegon
2,232 miles
39h 22m
24 stops
NightlifeConcerts & ShowsSpas & WellnessSights & LandmarksOther
FAQ
Frequently Asked Questions
What's the driving distance between Columbia and Knoxville?
The distance is 274 miles
What's the travel time between Columbia and Knoxville?
The driving time can vary depending on traffic conditions, but it is typically 5h 41m mins in normal traffic
What are some of the best cities to visit between Columbia and Knoxville?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Knoxville?
There are plenty! Here are some stops you shouldn’t miss on your way to Knoxville
What’s the weather like in Knoxville?
The weather in Knoxville is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Knoxville in January
Weather in Knoxville in February
Weather in Knoxville in March
Weather in Knoxville in April
Weather in Knoxville in May
Weather in Knoxville in June
Weather in Knoxville in July
Weather in Knoxville in August
Weather in Knoxville in September
Weather in Knoxville in October
Weather in Knoxville in November
Weather in Knoxville in December
Interested in a detailed plan for your time in Knoxville?
Plan your dream Knoxville trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Knoxville
A 2-day itinerary in Knoxville
A 3-day itinerary in Knoxville
A 4-day itinerary in Knoxville
A 5-day itinerary in Knoxville
A 6-day itinerary in Knoxville
Where else can I travel to if I'm starting my trip in Columbia?
We have a lot of great trip options for Columbia! See the links below for all the itineraries we created for you