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By Huuk Team

Road trip from Charleston to Knoxville

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ITINERARY

7h 7m370 miles26 stops
1
The Black Fedora Comedy Mystery Theatre
164 Church St, Charleston, SC 29401-3125
Live theatre featuring clean comic whodunit shows, volunteer audience participation, a la carte appetizers, homemade desserts, and drinks -- at the downtown City Market. “Uproarious entertainment” - Thrillist.com
2
Escape in 60
45 S Market St, Charleston, SC 29401-2004
Located in beautiful downtown Charleston at the heart of the Market on Market Street. In the middle of all of the action, attractions, restaurants, shops and bars. Escape In 60 is a fun, new entertainment concept to the Charleston. Each Escape Room is a real life adventure game designed for groups. Find hidden clues, solve riddles, puzzles, challenges and more. Take a break from all the Charleston history with an hour of interactive mystery!
3
Edmondston-Alston House
21 E Battery St, Charleston, SC 29401-2740
Constructed nearly 200 years ago, circa 1825, the Edmondston-Alston House presents a unique history of the people, both free and enslaved, who lived and labored on this property. Its collection of furniture, silver and decorative arts, largely original to those who owned the house, constitutes a rich, complex history of Charleston in the 19th century. Commanding a magnificent view of Charleston Harbor, the Edmondston-Alston House has witnessed many historic moments in the port city’s history. One of the oldest houses along the High Battery, it withstood the American Civil War, the Earthquake of 1886, and numerous hurricanes; it has survived to share a piece of Charleston history.
4
Greenville Zoo
150 Cleveland Park Dr, Greenville, SC 29601-3147
5
Still Point Wellness Spa
946 Tunnel Rd, Asheville, NC 28805
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
6
French Broad River Brewery
101 Fairview Rd, Asheville, NC 28803
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
7
Green Man Brewery
27 Buxton Ave, Asheville, NC 28801-4019
The Legendary Green Man has existed for centuries but it’s no myth that he’s been brewing great beer in Asheville since 1997. As home to one of North Carolina’s oldest breweries, tasting rooms and sour programs, Green Man has been producing some of the beer scene’s most iconic ales for many years. We are consistently recognized for our internationally loved traditional English styles and creative versions of the newest craft trends. Our brewers strive to bring innovative and exciting new flavors to all beer-loving folks. From Asheville’s first tasting room to one of Downtown Asheville’s largest tasting rooms, our storied growth has brought us to 2 brew houses, 3 tasting rooms, and 2 buildings. Our newest facility in Asheville’s South Slope Neighborhood is a 3 story, 22,000 sqft. packaging hall and specialty brewhouse including a “brewtique” and an indoor/outdoor taproom loft overlooking the Blue Ridge Mountains. When you visit, make sure to visit the original tasting room next door.
8
Lexington Glassworks
81 S Lexington Ave, Asheville, NC 28801-3309
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
9
Asheville Museum of Science
43 Patton Ave, Asheville, NC 28801-3314
The Asheville Museum of Science (AMOS) is Western North Carolina’s home for experiential science learning, discovery, and exploration. AMOS strives to spark the imagination and foster lifelong curiosity. We have plenty of science to come and explore including the Colburn Hall of Minerals, STEM lab, interactive panorama screen, Teratophoneus dinosaur skeleton and fossil dig, Southern Appalachian Forest tree climb, Terrabox elevation simulator, Toddler Nest, fun temporary exhibits, and museum store.
10
Grove Arcade
1 Page Ave, Asheville, NC 28801-2382
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
11
Asheville Pinball Museum
1 Battle Square Ste 1B, Asheville, NC 28801-2731
12
Ijams Nature Center
2915 Island Home Ave, Knoxville, TN 37920-2738
Ijams Nature Center is a 315-acre member- and visitor-supported nonprofit organization, where people of all ages can hike, bike, paddle, climb, learn, explore, or simply enjoy nature in Knoxville, TN. The grounds and trails are open every day from 8:00am until dusk. The Visitor Center, including exhibits, gift shop, offices, and restrooms are open during regular business hours. Admission to the park is free, and we gladly accept donations. Fees for programs and special events vary. Established in 1910 by the Ijams (pronounced "EYE-ams") family for bird-watchers and nature-lovers, Ijams Nature Center has been ranked one of Knoxville's top three attractions by TripAdvisor, winning their 2016 Certificate of Excellence . Your generous support is needed to continue the ongoing legacy for generations to come!
13
High Ground Park & River Bluff Wildlife Area
1000 Cherokee Trl, Knoxville, TN 37920-2327
Scenic birds eye view of Tennessee river, UT Knoxville, and Knoxville City. Short 0.42 miles hiking (both way less than 1 mile).
14
Hi Wire Brewing - Knoxville
906 Sevier Ave, Knoxville, TN 37920-1863
15
Knoxville Botanical Garden
2743 Wimpole Ave, Knoxville, TN 37914-5958
16
Krutch Park
504 Market St, Knoxville, TN 37902-2107
17
Peter Kern Library
407 Union Ave, Knoxville, TN 37902-2112
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
18
Muse Knoxville
516 N Beaman St, Knoxville, TN 37914-4410
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
19
PostModern Spirits
205 W Jackson Ave Suite 205, Knoxville, TN 37902-1018
PostModern Spirits in the heart of Knoxville's Old City open 7 days a week produces mindfully crafted spirits for the modern drinker. Visitors can savor PostModern's various offerings in the comfortable cocktail/tasting room or Thursday-Sunday join one of the fun distillery tours and tastings. Now producing several distinct varieties of gin, vodka, liqueurs like chamomile, cacao, elderberry, and bitter orange amaro arancia. Along with our American Single Malt Whiskey developed in collaboration with a local brewery!
20
The Mill and Mine
227 W Depot Ave, Knoxville, TN 37917-7521
21
Knoxville National Cemetery
939 Tyson St, Knoxville, TN 37917-7143
22
Cathedral of the Most Sacred Heart of Jesus
711 S Northshore Dr, Knoxville, TN 37919-7593
23
Smart Toys and Books
9700 Kingston Pike Ste 12, Knoxville, TN 37922-3384
24
Radius Rooftop Lounge
Embassy Suites By Hilton 507 S Gay St, Knoxville, TN 37902
25
Farragut Folklife Museum
11408 Municipal Center Dr, Knoxville, TN 37934-2830
26
THE CUTTING EDGE CLASSROOM
817 Herron Rd, Knoxville, TN 37932-3134
Educating East Tennessee in culinary skills and introducing fun into the kitchen! We provide safe and exciting classes for all skill levels from beginner to advanced! You will learn from the best Chefs in the area, meet new friends, cook like a pro, and enjoy what you have created! We also offer a variety of private group classes perfect for team building or other needs.
Customize this Trip

OVERVIEW

1
Start:The Black Fedora Comedy Mystery Theatre
Charleston, South Carolina·
4.5
(993) review
Live theatre featuring clean comic whodunit shows, volunteer audience participation, a la carte appetizers, homemade desserts, and drinks -- at the downtown City Market. “Uproarious entertainment” - Thrillist.com
164 Church St, Charleston, SC 29401-3125
2
Escape in 60
Charleston, South Carolina·
5.0
(975) review
Located in beautiful downtown Charleston at the heart of the Market on Market Street. In the middle of all of the action, attractions, restaurants, shops and bars. Escape In 60 is a fun, new entertainment concept to the Charleston. Each Escape Room is a real life adventure game designed for groups. Find hidden clues, solve riddles, puzzles, challenges and more. Take a break from all the Charleston history with an hour of interactive mystery!
45 S Market St, Charleston, SC 29401-2004
3
Edmondston-Alston House
Charleston, South Carolina·
4.5
(992) review
Constructed nearly 200 years ago, circa 1825, the Edmondston-Alston House presents a unique history of the people, both free and enslaved, who lived and labored on this property. Its collection of furniture, silver and decorative arts, largely original to those who owned the house, constitutes a rich, complex history of Charleston in the 19th century. Commanding a magnificent view of Charleston Harbor, the Edmondston-Alston House has witnessed many historic moments in the port city’s history. One of the oldest houses along the High Battery, it withstood the American Civil War, the Earthquake of 1886, and numerous hurricanes; it has survived to share a piece of Charleston history.
21 E Battery St, Charleston, SC 29401-2740
4
Greenville Zoo
Greenville, South Carolina·
4.0
(996) review
150 Cleveland Park Dr, Greenville, SC 29601-3147
5
Still Point Wellness Spa
Asheville, North Carolina·
5.0
(968) review
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
946 Tunnel Rd, Asheville, NC 28805
6
French Broad River Brewery
Asheville, North Carolina·
4.0
(98) review
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
101 Fairview Rd, Asheville, NC 28803
7
Green Man Brewery
Asheville, North Carolina·
4.5
(96) review
The Legendary Green Man has existed for centuries but it’s no myth that he’s been brewing great beer in Asheville since 1997. As home to one of North Carolina’s oldest breweries, tasting rooms and sour programs, Green Man has been producing some of the beer scene’s most iconic ales for many years. We are consistently recognized for our internationally loved traditional English styles and creative versions of the newest craft trends. Our brewers strive to bring innovative and exciting new flavors to all beer-loving folks. From Asheville’s first tasting room to one of Downtown Asheville’s largest tasting rooms, our storied growth has brought us to 2 brew houses, 3 tasting rooms, and 2 buildings. Our newest facility in Asheville’s South Slope Neighborhood is a 3 story, 22,000 sqft. packaging hall and specialty brewhouse including a “brewtique” and an indoor/outdoor taproom loft overlooking the Blue Ridge Mountains. When you visit, make sure to visit the original tasting room next door.
27 Buxton Ave, Asheville, NC 28801-4019
8
Lexington Glassworks
Asheville, North Carolina·
4.5
(983) review
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
81 S Lexington Ave, Asheville, NC 28801-3309
9
Asheville Museum of Science
Asheville, North Carolina·
3.5
(96) review
The Asheville Museum of Science (AMOS) is Western North Carolina’s home for experiential science learning, discovery, and exploration. AMOS strives to spark the imagination and foster lifelong curiosity. We have plenty of science to come and explore including the Colburn Hall of Minerals, STEM lab, interactive panorama screen, Teratophoneus dinosaur skeleton and fossil dig, Southern Appalachian Forest tree climb, Terrabox elevation simulator, Toddler Nest, fun temporary exhibits, and museum store.
43 Patton Ave, Asheville, NC 28801-3314
10
Grove Arcade
Asheville, North Carolina·
4.0
(987) review
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
1 Page Ave, Asheville, NC 28801-2382
11
Asheville Pinball Museum
Asheville, North Carolina·
4.5
(945) review
1 Battle Square Ste 1B, Asheville, NC 28801-2731
12
Ijams Nature Center
Knoxville, Tennessee·
4.5
(871) review
Ijams Nature Center is a 315-acre member- and visitor-supported nonprofit organization, where people of all ages can hike, bike, paddle, climb, learn, explore, or simply enjoy nature in Knoxville, TN. The grounds and trails are open every day from 8:00am until dusk. The Visitor Center, including exhibits, gift shop, offices, and restrooms are open during regular business hours. Admission to the park is free, and we gladly accept donations. Fees for programs and special events vary. Established in 1910 by the Ijams (pronounced "EYE-ams") family for bird-watchers and nature-lovers, Ijams Nature Center has been ranked one of Knoxville's top three attractions by TripAdvisor, winning their 2016 Certificate of Excellence . Your generous support is needed to continue the ongoing legacy for generations to come!
2915 Island Home Ave, Knoxville, TN 37920-2738
13
High Ground Park & River Bluff Wildlife Area
Knoxville, Tennessee·
4.5
(8) review
Scenic birds eye view of Tennessee river, UT Knoxville, and Knoxville City. Short 0.42 miles hiking (both way less than 1 mile).
1000 Cherokee Trl, Knoxville, TN 37920-2327
14
Hi Wire Brewing - Knoxville
Knoxville, Tennessee·
4.5
(9) review
906 Sevier Ave, Knoxville, TN 37920-1863
15
Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
16
Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
17
Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
407 Union Ave, Knoxville, TN 37902-2112
18
Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
516 N Beaman St, Knoxville, TN 37914-4410
19
PostModern Spirits
Knoxville, Tennessee·
5.0
(9) review
PostModern Spirits in the heart of Knoxville's Old City open 7 days a week produces mindfully crafted spirits for the modern drinker. Visitors can savor PostModern's various offerings in the comfortable cocktail/tasting room or Thursday-Sunday join one of the fun distillery tours and tastings. Now producing several distinct varieties of gin, vodka, liqueurs like chamomile, cacao, elderberry, and bitter orange amaro arancia. Along with our American Single Malt Whiskey developed in collaboration with a local brewery!
205 W Jackson Ave Suite 205, Knoxville, TN 37902-1018
20
The Mill and Mine
Knoxville, Tennessee·
5.0
(9) review
227 W Depot Ave, Knoxville, TN 37917-7521
21
Knoxville National Cemetery
Knoxville, Tennessee·
5.0
(9) review
939 Tyson St, Knoxville, TN 37917-7143
22
Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
23
Smart Toys and Books
Knoxville, Tennessee·
4.0
(8) review
9700 Kingston Pike Ste 12, Knoxville, TN 37922-3384
24
Radius Rooftop Lounge
Knoxville, Tennessee·
4.0
(9) review
Embassy Suites By Hilton 507 S Gay St, Knoxville, TN 37902
25
Farragut Folklife Museum
Knoxville, Tennessee·
4.5
(9) review
11408 Municipal Center Dr, Knoxville, TN 37934-2830
26
THE CUTTING EDGE CLASSROOM
Knoxville, Tennessee·
2.5
(8) review
Educating East Tennessee in culinary skills and introducing fun into the kitchen! We provide safe and exciting classes for all skill levels from beginner to advanced! You will learn from the best Chefs in the area, meet new friends, cook like a pro, and enjoy what you have created! We also offer a variety of private group classes perfect for team building or other needs.
817 Herron Rd, Knoxville, TN 37932-3134

CHECKLIST

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FAQ
Frequently Asked Questions
What's the driving distance between Charleston and Knoxville?
The distance is 370 miles
What's the travel time between Charleston and Knoxville?
The driving time can vary depending on traffic conditions, but it is typically 7h 7m mins in normal traffic
What are some of the best cities to visit between Charleston and Knoxville?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Knoxville?
There are plenty! Here are some stops you shouldn’t miss on your way to Knoxville
What’s the weather like in Knoxville?
The weather in Knoxville is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Knoxville in January
Weather in Knoxville in February
Weather in Knoxville in March
Weather in Knoxville in April
Weather in Knoxville in May
Weather in Knoxville in June
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Weather in Knoxville in December
Interested in a detailed plan for your time in Knoxville?
Plan your dream Knoxville trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Knoxville
A 2-day itinerary in Knoxville
A 3-day itinerary in Knoxville
A 4-day itinerary in Knoxville
A 5-day itinerary in Knoxville
A 6-day itinerary in Knoxville
Where else can I travel to if I'm starting my trip in Charleston?
We have a lot of great trip options for Charleston! See the links below for all the itineraries we created for you