Road trip from St. Louis to Knoxville
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Nightlife
Sights & Landmarks
Nature & Parks
Concerts & Shows
Museums
Spas & Wellness
Food & Drink
Show more (5+)
All Category
Nightlife
Sights & Landmarks
Nature & Parks
Concerts & Shows
Museums
Spas & Wellness
Food & Drink
Fun & Games
Water & Amusement Parks
Outdoor Activities
Shopping
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ITINERARY
8h 56m487 miles25 stops
1
The Highlands Golf & Tennis
2
Mr. Nice Guy
With the lowest prices, largest selection and highest quality of products in town, Mr. Nice Guy is the premier head shop for the St. Louis Metro Area. We are conveniently located near the Delmar Loop at 5892 Delmar Blvd and in South City at 2636 Cherokee St. At Mr. Nice Guy's you'll always find a friendly, knowledgeable staff willing to help you with all your smoking needs. We carry the largest selection of high-quality smoke supplies in the Metro St. Louis area. At both of our convenient locations, you'll get the best quality products at the lowest prices. You're sure to find what you need in our well-stocked stores. Looking for a new water pipe? Maybe an oil rig?Titantium nails? Or a sweet new vape pen? Mr. Nice Guy is your one-stop head shop for your smoking needs. We carry a wide variety of products, all available to you at the lowest of prices. Our products are high quality. Stop by one of our shops today. We guarantee you complete satisfaction with your product choice and purchase. We've got a great crew working with us to ensure your shopping experience with us, whether online or in one of our shops, is awesome. If you have any issues, please contact us.
3
St. Francis de Sales Church
4
The Dinner Detective
America's largest interactive comedy murder mystery dinner show! Solve a hilarious crime while you feast on a fantastic dinner. Just beware! The killer is hiding somewhere in the room, and you may find yourself as a Prime Suspect! The Dinner Detective also offers private events & shows that are customized to your group. Join us for a private event that your guests will talk about for months!
5
Tee Time Family Fun Center
6
Burdette Park
7
Willard Library
8
Evansville Brewhouse
9
Mo's House
10
Planet 3 Extreme Air Park
11
Tennessee State Museum
The Tennessee State Museum is located at the corner of Rosa L. Parks Blvd. and Jefferson Street at Bicentennial Capitol Mall State Park. It is designed to bring history to life. It includes a “Tennessee Time Tunnel” chronicling the state’s rich history and leading visitors though the Museum’s permanent collection, a hands-on children’s gallery, six rotating galleries, a state-of-the art digital learning center and a two-story Grand Hall. Exhibitions include significant artifacts related to the state’s history, along with displays of art, furniture, textiles, and photographs produced by Tennesseans. The Museum's Civil War holdings of uniforms, battle flags and weapons are among the finest in the nation.There is no admission charge for visitors. Hours are subject to change. Please check our website at tnmuseum.org for the most up to date information on parking, exhibitions and events.
12
Bicentennial Capitol Mall State Park
This 19 acre park in the heart of Nashville serves as a monument to the bicentennial celebration of the State of Tennessee. This park offers plenty of opportunities to learn about the long history of Tennessee while having a great experience in a beautiful green space. More information on this park and many more can be found at the TN State Parks website.
13
Jackalope Brewing Company - The Ranch
Jackalope Brewing Company's taproom and brewery The Ranch offers locally hand-crafted beers, brewery tours, small bites, and a dog-friendly outdoor patio.
14
Amber Falls Winery Nashville
Amber Falls Winery Nashville is proud and excited to be the first and only winery at Opry Mills Mall! We are a satellite store for Amber Falls Winery & Cellars in Hampshire, TN. Our mission is to bring the same exceptional customer service and award-winning wine to Nashville! We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. Something new that we are excited about is selling our delicious WineTeaZers in growlers! Enjoy it anywhere and then bring your growler back for more! So swing by and taste some of our wine, sit and sip on a glass with friends and then take a few bottles home to enjoy!
15
Lane Motor Museum
Lane Motor Museum in Nashville features the largest European collection of cars and motorcycles in the United States. Admission for adults aged 18-64 is $15; Admission for Youths aged 6-17 is $3; Admission for seniors 65+ is $10; Children under 5 are always free. There is plenty of FREE parking.
16
Larry Keeton Theatre
17
Athenian Luxe Spa & Bar
18
Radius Rooftop Lounge
19
Cathedral of the Most Sacred Heart of Jesus
20
Knoxville National Cemetery
21
The Mill and Mine
22
Peter Kern Library
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
23
Krutch Park
24
Muse Knoxville
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
25
Knoxville Botanical Garden
Customize this Trip
OVERVIEW
1
Start:The Highlands Golf & Tennis
Saint Louis, Missouri·
3.0
(9) review
5163 Clayton Ave, Saint Louis, MO 63110-1423
2
Start:Mr. Nice Guy
Saint Louis, Missouri·
3.5
(9) review
With the lowest prices, largest selection and highest quality of products in town, Mr. Nice Guy is the premier head shop for the St. Louis Metro Area. We are conveniently located near the Delmar Loop at 5892 Delmar Blvd and in South City at 2636 Cherokee St. At Mr. Nice Guy's you'll always find a friendly, knowledgeable staff willing to help you with all your smoking needs. We carry the largest selection of high-quality smoke supplies in the Metro St. Louis area. At both of our convenient locations, you'll get the best quality products at the lowest prices. You're sure to find what you need in our well-stocked stores. Looking for a new water pipe? Maybe an oil rig?Titantium nails? Or a sweet new vape pen? Mr. Nice Guy is your one-stop head shop for your smoking needs. We carry a wide variety of products, all available to you at the lowest of prices. Our products are high quality. Stop by one of our shops today. We guarantee you complete satisfaction with your product choice and purchase. We've got a great crew working with us to ensure your shopping experience with us, whether online or in one of our shops, is awesome. If you have any issues, please contact us.
3
Start:St. Francis de Sales Church
Saint Louis, Missouri·
5.0
(9) review
2653 Ohio Ave, Saint Louis, MO 63118-1594
4
Start:The Dinner Detective
Saint Louis, Missouri·
4.5
(9) review
America's largest interactive comedy murder mystery dinner show! Solve a hilarious crime while you feast on a fantastic dinner. Just beware! The killer is hiding somewhere in the room, and you may find yourself as a Prime Suspect! The Dinner Detective also offers private events & shows that are customized to your group. Join us for a private event that your guests will talk about for months!
5
Start:Tee Time Family Fun Center
Saint Louis, Missouri·
2.5
(9) review
4631 Lemay Ferry Rd, Saint Louis, MO 63129-1615
6
Start:Burdette Park
Evansville, Indiana·
4.0
(95) review
5301 Nurrenbern Rd, Evansville, IN 47712-9368
7
Start:Willard Library
Evansville, Indiana·
4.5
(97) review
21 N 1st Ave, Evansville, IN 47710-1294
8
Start:Evansville Brewhouse
Evansville, Indiana·
4.5
(9) review
56 Adams Ave, Evansville, IN 47713-1310
9
Start:Mo's House
Evansville, Indiana·
4.5
(9) review
1114 Parrett St, Evansville, IN 47713-1344
10
Start:Planet 3 Extreme Air Park
Clarksville, Tennessee·
4.0
(9) review
310 Needmore Rd, Clarksville, TN 37040-6640
11
Start:Tennessee State Museum
Nashville, Davidson County, Tennessee·
4.5
(997) review
The Tennessee State Museum is located at the corner of Rosa L. Parks Blvd. and Jefferson Street at Bicentennial Capitol Mall State Park. It is designed to bring history to life. It includes a “Tennessee Time Tunnel” chronicling the state’s rich history and leading visitors though the Museum’s permanent collection, a hands-on children’s gallery, six rotating galleries, a state-of-the art digital learning center and a two-story Grand Hall. Exhibitions include significant artifacts related to the state’s history, along with displays of art, furniture, textiles, and photographs produced by Tennesseans. The Museum's Civil War holdings of uniforms, battle flags and weapons are among the finest in the nation.There is no admission charge for visitors. Hours are subject to change. Please check our website at tnmuseum.org for the most up to date information on parking, exhibitions and events.
12
Start:Bicentennial Capitol Mall State Park
Nashville, Davidson County, Tennessee·
4.5
(969) review
This 19 acre park in the heart of Nashville serves as a monument to the bicentennial celebration of the State of Tennessee. This park offers plenty of opportunities to learn about the long history of Tennessee while having a great experience in a beautiful green space. More information on this park and many more can be found at the TN State Parks website.
13
Start:Jackalope Brewing Company - The Ranch
Nashville, Davidson County, Tennessee·
4.5
(9) review
Jackalope Brewing Company's taproom and brewery The Ranch offers locally hand-crafted beers, brewery tours, small bites, and a dog-friendly outdoor patio.
14
Start:Amber Falls Winery Nashville
Nashville, Davidson County, Tennessee·
4.5
(9) review
Amber Falls Winery Nashville is proud and excited to be the first and only winery at Opry Mills Mall! We are a satellite store for Amber Falls Winery & Cellars in Hampshire, TN. Our mission is to bring the same exceptional customer service and award-winning wine to Nashville! We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. Something new that we are excited about is selling our delicious WineTeaZers in growlers! Enjoy it anywhere and then bring your growler back for more! So swing by and taste some of our wine, sit and sip on a glass with friends and then take a few bottles home to enjoy!
15
Start:Lane Motor Museum
Nashville, Davidson County, Tennessee·
4.5
(971) review
Lane Motor Museum in Nashville features the largest European collection of cars and motorcycles in the United States. Admission for adults aged 18-64 is $15; Admission for Youths aged 6-17 is $3; Admission for seniors 65+ is $10; Children under 5 are always free. There is plenty of FREE parking.
16
Start:Larry Keeton Theatre
Nashville, Davidson County, Tennessee·
4.5
(9) review
108 Donelson Pike At the Fifty Forward Center, Nashville, TN 37214-2902
17
Start:Athenian Luxe Spa & Bar
Nashville, Davidson County, Tennessee·
4.0
(9) review
15537 Old Hickory Blvd, Nashville, TN 37211-6224
18
Start:Radius Rooftop Lounge
Knoxville, Tennessee·
4.0
(9) review
Embassy Suites By Hilton 507 S Gay St, Knoxville, TN 37902
19
Start:Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
20
Start:Knoxville National Cemetery
Knoxville, Tennessee·
5.0
(9) review
939 Tyson St, Knoxville, TN 37917-7143
21
Start:The Mill and Mine
Knoxville, Tennessee·
5.0
(9) review
227 W Depot Ave, Knoxville, TN 37917-7521
22
Start:Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
23
Start:Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
24
Start:Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
25
Start:Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
CHECKLIST
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Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
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FAQ
Frequently Asked Questions
What's the driving distance between St. Louis and Knoxville?
The distance is 487 miles
What's the travel time between St. Louis and Knoxville?
The driving time can vary depending on traffic conditions, but it is typically 8h 56m mins in normal traffic
What are some of the best cities to visit between St. Louis and Knoxville?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Knoxville?
There are plenty! Here are some stops you shouldn’t miss on your way to Knoxville
What’s the weather like in Knoxville?
The weather in Knoxville is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Knoxville in January
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Weather in Knoxville in December
Interested in a detailed plan for your time in Knoxville?
Plan your dream Knoxville trip with our daily itineraries featuring must-see attractions! See them here!
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Where else can I travel to if I'm starting my trip in St. Louis?
We have a lot of great trip options for St. Louis! See the links below for all the itineraries we created for you