Road trip from St. Louis to Indianapolis
All Category
Fun & Games
Museums
Sights & Landmarks
Food & Drink
Nightlife
Concerts & Shows
Outdoor Activities
Show more (5+)
All Category
Fun & Games
Museums
Sights & Landmarks
Food & Drink
Nightlife
Concerts & Shows
Outdoor Activities
Shopping
Nature & Parks
Water & Amusement Parks
Spas & Wellness
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ITINERARY
4h 42m246 miles17 stops
1
The Highlands Golf & Tennis
2
Modern Brewery
3
Fairgrounds Park
4
Mr. Nice Guy
With the lowest prices, largest selection and highest quality of products in town, Mr. Nice Guy is the premier head shop for the St. Louis Metro Area. We are conveniently located near the Delmar Loop at 5892 Delmar Blvd and in South City at 2636 Cherokee St. At Mr. Nice Guy's you'll always find a friendly, knowledgeable staff willing to help you with all your smoking needs. We carry the largest selection of high-quality smoke supplies in the Metro St. Louis area. At both of our convenient locations, you'll get the best quality products at the lowest prices. You're sure to find what you need in our well-stocked stores. Looking for a new water pipe? Maybe an oil rig?Titantium nails? Or a sweet new vape pen? Mr. Nice Guy is your one-stop head shop for your smoking needs. We carry a wide variety of products, all available to you at the lowest of prices. Our products are high quality. Stop by one of our shops today. We guarantee you complete satisfaction with your product choice and purchase. We've got a great crew working with us to ensure your shopping experience with us, whether online or in one of our shops, is awesome. If you have any issues, please contact us.
5
St. Francis de Sales Church
6
Trust
In the shadow of the St. Louis Arch, the Missisippi Valley Trust Company has proudly stood at the corner of 4th and Pine since 1896. While the city transformed around it, within these walls time stood still. Today we invite you back, to old-fashioned charm, timeless hospitality, and a modern twist.
7
Oakland House Museum
Tucked away in Affton, Missouri stands the country home of the pioneer banker, Louis A. Benoist. Today, his mansion has been completely restored today to its original beauty from 1853. The house, now a historic museum, is owned and maintained by the Affton Historical Society. They began Oakland's restoration back in the early 1970s. Visit us for a historic tour of one of Affton's most hidden gems that was saved and still stands today. View our calendar for upcoming events and open house times.
8
The Dinner Detective
America's largest interactive comedy murder mystery dinner show! Solve a hilarious crime while you feast on a fantastic dinner. Just beware! The killer is hiding somewhere in the room, and you may find yourself as a Prime Suspect! The Dinner Detective also offers private events & shows that are customized to your group. Join us for a private event that your guests will talk about for months!
9
Thomas Sappington House Museum
10
Tee Time Family Fun Center
11
Thies Farm & Greenhouses
A farm right here in the city! Homegrown produce direct from the fields and plants grown in greenhouses on site.
12
Escapology Greenwood
Greenwood's premium real life escape game experience. Play in private teams of 2-8 players in exciting games and search carefully for clues, solve puzzles and try to escape within 60 minutes. Do you have what it takes?
13
Centennial Park Champaign
14
DECEPTION
DECEPTION is a magic & mind reading show, hosted by magician David Ranalli. David creates an unforgettable evening by combining world-class sleight of hand, witty banter, and mysteries of the mind. Guests are invited into an intimate, cabaret theater where surprises lurk in every corner. Perfect as a date night, group event, and for the hardcore magic fan.
15
Smiley
Smiley is a huge 25,000 sq foot facility in Castleton filled with the latest Virtual Reality technology. We have very rare and unique interactive games and rides for children of all ages. Our playgrounds are for age 9 months to 10 years old and our VR spaces are for ages 9 years and up! We also have an enormous indoor playground with trampoline basketball, tubes & slides, rock-climbing, obstacle
16
Indianapolis Salt Cave & Halotherapy Center
Step into 9 tons of salt used to recreate the environmental conditions found in a natural underground salt mine. This man-made salt cave, creates the ideal atmospheric breathing condition. Relax, breathe deep and rejuvenate in the Indianapolis Salt Cave and Halotherapy Center.
17
The Grill
Customize this Trip
OVERVIEW
1
Start:The Highlands Golf & Tennis
Saint Louis, Missouri·
3.0
(9) review
5163 Clayton Ave, Saint Louis, MO 63110-1423
2
Start:Modern Brewery
Saint Louis, Missouri·
4.5
(9) review
5231 Manchester Ave, Saint Louis, MO 63110-2015
3
Start:Fairgrounds Park
Saint Louis, Missouri·
3.0
(9) review
North Grand and Natural Bridge, Saint Louis, MO 63110
4
Start:Mr. Nice Guy
Saint Louis, Missouri·
3.5
(9) review
With the lowest prices, largest selection and highest quality of products in town, Mr. Nice Guy is the premier head shop for the St. Louis Metro Area. We are conveniently located near the Delmar Loop at 5892 Delmar Blvd and in South City at 2636 Cherokee St. At Mr. Nice Guy's you'll always find a friendly, knowledgeable staff willing to help you with all your smoking needs. We carry the largest selection of high-quality smoke supplies in the Metro St. Louis area. At both of our convenient locations, you'll get the best quality products at the lowest prices. You're sure to find what you need in our well-stocked stores. Looking for a new water pipe? Maybe an oil rig?Titantium nails? Or a sweet new vape pen? Mr. Nice Guy is your one-stop head shop for your smoking needs. We carry a wide variety of products, all available to you at the lowest of prices. Our products are high quality. Stop by one of our shops today. We guarantee you complete satisfaction with your product choice and purchase. We've got a great crew working with us to ensure your shopping experience with us, whether online or in one of our shops, is awesome. If you have any issues, please contact us.
5
Start:St. Francis de Sales Church
Saint Louis, Missouri·
5.0
(9) review
2653 Ohio Ave, Saint Louis, MO 63118-1594
6
Start:Trust
Saint Louis, Missouri·
4.5
(9) review
In the shadow of the St. Louis Arch, the Missisippi Valley Trust Company has proudly stood at the corner of 4th and Pine since 1896. While the city transformed around it, within these walls time stood still. Today we invite you back, to old-fashioned charm, timeless hospitality, and a modern twist.
7
Start:Oakland House Museum
Saint Louis, Missouri·
4.5
(9) review
Tucked away in Affton, Missouri stands the country home of the pioneer banker, Louis A. Benoist. Today, his mansion has been completely restored today to its original beauty from 1853. The house, now a historic museum, is owned and maintained by the Affton Historical Society. They began Oakland's restoration back in the early 1970s. Visit us for a historic tour of one of Affton's most hidden gems that was saved and still stands today. View our calendar for upcoming events and open house times.
8
Start:The Dinner Detective
Saint Louis, Missouri·
4.5
(9) review
America's largest interactive comedy murder mystery dinner show! Solve a hilarious crime while you feast on a fantastic dinner. Just beware! The killer is hiding somewhere in the room, and you may find yourself as a Prime Suspect! The Dinner Detective also offers private events & shows that are customized to your group. Join us for a private event that your guests will talk about for months!
9
Start:Thomas Sappington House Museum
Crestwood, Saint Louis, Missouri·
4.5
(9) review
1015 S Sappington Rd, Crestwood, Saint Louis, MO 63126
10
Start:Tee Time Family Fun Center
Saint Louis, Missouri·
2.5
(9) review
4631 Lemay Ferry Rd, Saint Louis, MO 63129-1615
11
Start:Thies Farm & Greenhouses
Saint Louis, Missouri·
3.5
(9) review
A farm right here in the city! Homegrown produce direct from the fields and plants grown in greenhouses on site.
12
Start:Escapology Greenwood
Indianapolis, Indiana·
5.0
(9) review
Greenwood's premium real life escape game experience. Play in private teams of 2-8 players in exciting games and search carefully for clues, solve puzzles and try to escape within 60 minutes. Do you have what it takes?
13
Start:Centennial Park Champaign
Champaign, Champaign-Urbana, Illinois·
4.5
(9) review
Kirby St Crescent Dr, Champaign, Champaign-Urbana, IL
14
Start:DECEPTION
Indianapolis, Indiana·
4.5
(9) review
DECEPTION is a magic & mind reading show, hosted by magician David Ranalli. David creates an unforgettable evening by combining world-class sleight of hand, witty banter, and mysteries of the mind. Guests are invited into an intimate, cabaret theater where surprises lurk in every corner. Perfect as a date night, group event, and for the hardcore magic fan.
15
Start:Smiley
Indianapolis, Indiana·
3.5
(9) review
Smiley is a huge 25,000 sq foot facility in Castleton filled with the latest Virtual Reality technology. We have very rare and unique interactive games and rides for children of all ages. Our playgrounds are for age 9 months to 10 years old and our VR spaces are for ages 9 years and up! We also have an enormous indoor playground with trampoline basketball, tubes & slides, rock-climbing, obstacle
16
Start:Indianapolis Salt Cave & Halotherapy Center
Indianapolis, Indiana·
5.0
(9) review
Step into 9 tons of salt used to recreate the environmental conditions found in a natural underground salt mine. This man-made salt cave, creates the ideal atmospheric breathing condition. Relax, breathe deep and rejuvenate in the Indianapolis Salt Cave and Halotherapy Center.
17
Start:The Grill
Indianapolis, Indiana·
3.5
(9) review
9755 Fall Creek Rd, Indianapolis, IN 46256-4713
CHECKLIST
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Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
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FAQ
Frequently Asked Questions
What's the driving distance between St. Louis and Indianapolis?
The distance is 246 miles
What's the travel time between St. Louis and Indianapolis?
The driving time can vary depending on traffic conditions, but it is typically 4h 42m mins in normal traffic
What are some of the best cities to visit between St. Louis and Indianapolis?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Indianapolis?
There are plenty! Here are some stops you shouldn’t miss on your way to Indianapolis
What’s the weather like in Indianapolis?
The weather in Indianapolis is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Indianapolis in January
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Interested in a detailed plan for your time in Indianapolis?
Plan your dream Indianapolis trip with our daily itineraries featuring must-see attractions! See them here!
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Where else can I travel to if I'm starting my trip in St. Louis?
We have a lot of great trip options for St. Louis! See the links below for all the itineraries we created for you