logo
By Huuk Team

Road trip from St. Louis to Charleston

All Category
iconMuseums
iconConcerts & Shows
iconBoat Tours & Water Sports
iconOutdoor Activities
iconFood & Drink
iconSpas & Wellness
iconSights & Landmarks
Show more (5+)

ITINERARY

16h 1m856 miles21 stops
1
The Highlands Golf & Tennis
5163 Clayton Ave, Saint Louis, MO 63110-1423
2
Tee Time Family Fun Center
4631 Lemay Ferry Rd, Saint Louis, MO 63129-1615
3
Burdette Park
5301 Nurrenbern Rd, Evansville, IN 47712-9368
4
Willard Library
21 N 1st Ave, Evansville, IN 47710-1294
5
Tennessee State Museum
1000 Rosa L Parks Blvd, Nashville, TN 37208-2624
The Tennessee State Museum is located at the corner of Rosa L. Parks Blvd. and Jefferson Street at Bicentennial Capitol Mall State Park. It is designed to bring history to life. It includes a “Tennessee Time Tunnel” chronicling the state’s rich history and leading visitors though the Museum’s permanent collection, a hands-on children’s gallery, six rotating galleries, a state-of-the art digital learning center and a two-story Grand Hall. Exhibitions include significant artifacts related to the state’s history, along with displays of art, furniture, textiles, and photographs produced by Tennesseans. The Museum's Civil War holdings of uniforms, battle flags and weapons are among the finest in the nation.There is no admission charge for visitors. Hours are subject to change. Please check our website at tnmuseum.org for the most up to date information on parking, exhibitions and events.
6
Bicentennial Capitol Mall State Park
600 James Robertson Pkwy, Nashville, TN 37243-3081
This 19 acre park in the heart of Nashville serves as a monument to the bicentennial celebration of the State of Tennessee. This park offers plenty of opportunities to learn about the long history of Tennessee while having a great experience in a beautiful green space. More information on this park and many more can be found at the TN State Parks website.
7
Jackalope Brewing Company - The Ranch
429B Houston St, Nashville, TN 37203-4832
Jackalope Brewing Company's taproom and brewery The Ranch offers locally hand-crafted beers, brewery tours, small bites, and a dog-friendly outdoor patio.
8
Amber Falls Winery Nashville
349 Opry Mills Dr Suite 751A, Nashville, TN 37214-2437
Amber Falls Winery Nashville is proud and excited to be the first and only winery at Opry Mills Mall! We are a satellite store for Amber Falls Winery & Cellars in Hampshire, TN. Our mission is to bring the same exceptional customer service and award-winning wine to Nashville! We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. Something new that we are excited about is selling our delicious WineTeaZers in growlers! Enjoy it anywhere and then bring your growler back for more! So swing by and taste some of our wine, sit and sip on a glass with friends and then take a few bottles home to enjoy!
9
Lane Motor Museum
702 Murfreesboro Pike, Nashville, TN 37210-4522
Lane Motor Museum in Nashville features the largest European collection of cars and motorcycles in the United States. Admission for adults aged 18-64 is $15; Admission for Youths aged 6-17 is $3; Admission for seniors 65+ is $10; Children under 5 are always free. There is plenty of FREE parking.
10
Cathedral of the Most Sacred Heart of Jesus
711 S Northshore Dr, Knoxville, TN 37919-7593
11
Peter Kern Library
407 Union Ave, Knoxville, TN 37902-2112
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
12
Krutch Park
504 Market St, Knoxville, TN 37902-2107
13
Muse Knoxville
516 N Beaman St, Knoxville, TN 37914-4410
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
14
Knoxville Botanical Garden
2743 Wimpole Ave, Knoxville, TN 37914-5958
15
Grove Arcade
1 Page Ave, Asheville, NC 28801-2382
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
16
Lexington Glassworks
81 S Lexington Ave, Asheville, NC 28801-3309
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
17
French Broad River Brewery
101 Fairview Rd, Asheville, NC 28803
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
18
Still Point Wellness Spa
946 Tunnel Rd, Asheville, NC 28805
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
19
Greenville Zoo
150 Cleveland Park Dr, Greenville, SC 29601-3147
20
The Black Fedora Comedy Mystery Theatre
164 Church St, Charleston, SC 29401-3125
Live theatre featuring clean comic whodunit shows, volunteer audience participation, a la carte appetizers, homemade desserts, and drinks -- at the downtown City Market. “Uproarious entertainment” - Thrillist.com
21
Edmondston-Alston House
21 E Battery St, Charleston, SC 29401-2740
Constructed nearly 200 years ago, circa 1825, the Edmondston-Alston House presents a unique history of the people, both free and enslaved, who lived and labored on this property. Its collection of furniture, silver and decorative arts, largely original to those who owned the house, constitutes a rich, complex history of Charleston in the 19th century. Commanding a magnificent view of Charleston Harbor, the Edmondston-Alston House has witnessed many historic moments in the port city’s history. One of the oldest houses along the High Battery, it withstood the American Civil War, the Earthquake of 1886, and numerous hurricanes; it has survived to share a piece of Charleston history.
Customize this Trip

OVERVIEW

1
Start:The Highlands Golf & Tennis
Saint Louis, Missouri·
3.0
(9) review
5163 Clayton Ave, Saint Louis, MO 63110-1423
2
Tee Time Family Fun Center
Saint Louis, Missouri·
2.5
(9) review
4631 Lemay Ferry Rd, Saint Louis, MO 63129-1615
3
Burdette Park
Evansville, Indiana·
4.0
(95) review
5301 Nurrenbern Rd, Evansville, IN 47712-9368
4
Willard Library
Evansville, Indiana·
4.5
(97) review
21 N 1st Ave, Evansville, IN 47710-1294
5
Tennessee State Museum
Nashville, Davidson County, Tennessee·
4.5
(997) review
The Tennessee State Museum is located at the corner of Rosa L. Parks Blvd. and Jefferson Street at Bicentennial Capitol Mall State Park. It is designed to bring history to life. It includes a “Tennessee Time Tunnel” chronicling the state’s rich history and leading visitors though the Museum’s permanent collection, a hands-on children’s gallery, six rotating galleries, a state-of-the art digital learning center and a two-story Grand Hall. Exhibitions include significant artifacts related to the state’s history, along with displays of art, furniture, textiles, and photographs produced by Tennesseans. The Museum's Civil War holdings of uniforms, battle flags and weapons are among the finest in the nation.There is no admission charge for visitors. Hours are subject to change. Please check our website at tnmuseum.org for the most up to date information on parking, exhibitions and events.
1000 Rosa L Parks Blvd, Nashville, TN 37208-2624
6
Bicentennial Capitol Mall State Park
Nashville, Davidson County, Tennessee·
4.5
(969) review
This 19 acre park in the heart of Nashville serves as a monument to the bicentennial celebration of the State of Tennessee. This park offers plenty of opportunities to learn about the long history of Tennessee while having a great experience in a beautiful green space. More information on this park and many more can be found at the TN State Parks website.
600 James Robertson Pkwy, Nashville, TN 37243-3081
7
Jackalope Brewing Company - The Ranch
Nashville, Davidson County, Tennessee·
4.5
(9) review
Jackalope Brewing Company's taproom and brewery The Ranch offers locally hand-crafted beers, brewery tours, small bites, and a dog-friendly outdoor patio.
429B Houston St, Nashville, TN 37203-4832
8
Amber Falls Winery Nashville
Nashville, Davidson County, Tennessee·
4.5
(9) review
Amber Falls Winery Nashville is proud and excited to be the first and only winery at Opry Mills Mall! We are a satellite store for Amber Falls Winery & Cellars in Hampshire, TN. Our mission is to bring the same exceptional customer service and award-winning wine to Nashville! We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. We offer wine tastings, wine by the glass and also sell our fabulous wine by the bottle. Something new that we are excited about is selling our delicious WineTeaZers in growlers! Enjoy it anywhere and then bring your growler back for more! So swing by and taste some of our wine, sit and sip on a glass with friends and then take a few bottles home to enjoy!
349 Opry Mills Dr Suite 751A, Nashville, TN 37214-2437
9
Lane Motor Museum
Nashville, Davidson County, Tennessee·
4.5
(971) review
Lane Motor Museum in Nashville features the largest European collection of cars and motorcycles in the United States. Admission for adults aged 18-64 is $15; Admission for Youths aged 6-17 is $3; Admission for seniors 65+ is $10; Children under 5 are always free. There is plenty of FREE parking.
702 Murfreesboro Pike, Nashville, TN 37210-4522
10
Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
11
Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
407 Union Ave, Knoxville, TN 37902-2112
12
Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
13
Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
516 N Beaman St, Knoxville, TN 37914-4410
14
Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
15
Grove Arcade
Asheville, North Carolina·
4.0
(987) review
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
1 Page Ave, Asheville, NC 28801-2382
16
Lexington Glassworks
Asheville, North Carolina·
4.5
(983) review
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
81 S Lexington Ave, Asheville, NC 28801-3309
17
French Broad River Brewery
Asheville, North Carolina·
4.0
(98) review
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
101 Fairview Rd, Asheville, NC 28803
18
Still Point Wellness Spa
Asheville, North Carolina·
5.0
(968) review
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
946 Tunnel Rd, Asheville, NC 28805
19
Greenville Zoo
Greenville, South Carolina·
4.0
(996) review
150 Cleveland Park Dr, Greenville, SC 29601-3147
20
The Black Fedora Comedy Mystery Theatre
Charleston, South Carolina·
4.5
(993) review
Live theatre featuring clean comic whodunit shows, volunteer audience participation, a la carte appetizers, homemade desserts, and drinks -- at the downtown City Market. “Uproarious entertainment” - Thrillist.com
164 Church St, Charleston, SC 29401-3125
21
Edmondston-Alston House
Charleston, South Carolina·
4.5
(992) review
Constructed nearly 200 years ago, circa 1825, the Edmondston-Alston House presents a unique history of the people, both free and enslaved, who lived and labored on this property. Its collection of furniture, silver and decorative arts, largely original to those who owned the house, constitutes a rich, complex history of Charleston in the 19th century. Commanding a magnificent view of Charleston Harbor, the Edmondston-Alston House has witnessed many historic moments in the port city’s history. One of the oldest houses along the High Battery, it withstood the American Civil War, the Earthquake of 1886, and numerous hurricanes; it has survived to share a piece of Charleston history.
21 E Battery St, Charleston, SC 29401-2740

CHECKLIST

icon
GPS device or app
icon
Download Offline Map
icon
Car charger and portable battery
icon
Water bottles and snacks
icon
Travel pillow and blanket
icon
Sunglasses and sunscreen
icon
First-aid kit
icon
Trash bags
icon
Hand sanitizer and wet wipes
icon
Driver’s license and vehicle registration
icon
Cash and cards
icon
Camera or smartphone
Unlock Effortless Travel Planning
Create your dream trip in minutes by this prompt. Try now!
FAQ
Frequently Asked Questions
What's the driving distance between St. Louis and Charleston?
The distance is 856 miles
What's the travel time between St. Louis and Charleston?
The driving time can vary depending on traffic conditions, but it is typically 16h 1m mins in normal traffic
What are some of the best cities to visit between St. Louis and Charleston?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Charleston?
There are plenty! Here are some stops you shouldn’t miss on your way to Charleston
What’s the weather like in Charleston?
The weather in Charleston is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Charleston in January
Weather in Charleston in February
Weather in Charleston in March
Weather in Charleston in April
Weather in Charleston in May
Weather in Charleston in June
Weather in Charleston in July
Weather in Charleston in August
Weather in Charleston in September
Weather in Charleston in October
Weather in Charleston in November
Weather in Charleston in December
Interested in a detailed plan for your time in Charleston?
Plan your dream Charleston trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Charleston
A 2-day itinerary in Charleston
A 3-day itinerary in Charleston
A 4-day itinerary in Charleston
A 5-day itinerary in Charleston
A 6-day itinerary in Charleston
Where else can I travel to if I'm starting my trip in St. Louis?
We have a lot of great trip options for St. Louis! See the links below for all the itineraries we created for you