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By Huuk Team

Road trip from Lancaster to Sioux Falls

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iconNature & Parks
iconMuseums
iconSights & Landmarks
iconFun & Games
iconShopping
iconNightlife

ITINERARY

23h 27m1,272 miles15 stops
1
Reading Rocks
George St., Reading, PA
2
Pennsylvania State Capitol
Third Street ird Street d Street Street reet et, Harrisburg, PA 17101
Teddy Roosevelt declared that this Italian Renaissance-style building was “the handsomest building I ever saw”. Indeed, the State Capitol, with its vaulted dome and grand staircase and the murals and painted floors inside, is thing to behold.
3
Cathedral of Learning
4200 5th Ave., Pittsburgh, PA 15260
4
Point State Park
601 Commonwealth Pl Bldg A, Pittsburgh, PA 15222
Serving as a key strategic spot during the French and Indian War, this National Historic Landmark and park offer stunning views of the city and a variety of outdoor recreation.
5
Lock 3
200 S Main St, Akron, OH 44308-1315
6
Rock & Roll Hall of Fame
1100 Rock and Roll Blvd Main Terminal, Cleveland, OH 44114-1023
Headquartered in a boldly designed building on Lake Erie's shore, The Rock and Roll Hall of Fame is a 150,000-square-foot museum featuring ever-changing exhibits documenting the history of rock and roll, from Elvis to our days. You’ll see hundreds of original artifacts, from Jimi Hendrix outfits to The Beatles’ handwritten lyrics. Experience the excitement of a Rock Hall induction night at the Power of Rock Experience or have your very own jam session at the Garage. You can also watch a concert while you're here, so check out the Rock Hall’s schedule and plan ahead. – Tripadvisor
7
Allen County War Memorial Coliseum
4000 Parnell Ave, Fort Wayne, IN 46805-1414
8
Michigan Avenue Bridge
333 Michigan Ave, Chicago, IL 60601-3901
The view from the bridge is one of the best vistas the city has to offer.
9
Boystown
Chicago, IL
Located in Chicago's North Side, this vibrant neighborhood is known for its exciting nightlife and for being one of the largest LGBTQIA+ communities in the city. It's the host of the annual Chicago Pride Parade, and a must-see in the area is the Legacy Walk on Halsted Street, where you can learn about the contributions of the LGBTQIA+ community while admiring the colorful street art and rainbow crosswalks. Check out the unique shops and then grab a bite at one of the area's delicious Thai or Mexican restaurants. At night, visit one of the neighborhood's bars to enjoy a drag show, concert, and tasty cocktail. Consider taking a food or walking tour of Chicago that stops by Boystown. – Tripadvisor
10
Wrigley Field
1060 W. Addison St., Chicago, IL 60613-4566
Get a behind-the-scenes look at the legendary home of the Chicago Cubs with Wrigley Field Tours. Built in 1914, this must-see Chicago attraction houses more than 100 years of history. New this year, fans can join us on a non-gameday Ivy Tour which includes the opportunity to take a photo in front of Wrigley Field’s historic ivy wall.
11
Alliant Energy Center
1919 Alliant Energy Center Way, Madison, WI 53713-1400
Our premier downtown multi-venue complex features four unique and versatile venues: Veterans Memorial Coliseum, Exhibition Hall, the New Holland Pavilions, and Willow Island. A top choice for expositions, conventions, meetings, concerts, sporting events, ag events, and much more, the Alliant Energy Center complex is a one-stop-shop for all your events. Ample parking, mouthwatering catering, dedicated staff, and a full range of rental equipment & high speed internet make AEC an event planners delight!
12
First Unitarian Meeting House of Madison
900 University Bay Dr, Madison, WI 53705-2298
13
Stockyards Ag Experience
301 E Falls Park Dr Main Entrance is on the South side of the building., Sioux Falls, SD 57104-5962
We deepen the connection between agriculture to everyday life with learning experiences that highlight history, science, culture and economic impact. We educate through interactive displays, hands-on learning and vibrant stories.
14
Stogeez Cigar Lounge
201 E 11th St, Sioux Falls, SD 57104-6748
15
Little Wine Cellar Co
2390 S Louise Ave, Sioux Falls, SD 57106-4337
Customize this Trip

OVERVIEW

1
Start:Reading Rocks
Reading, Pennsylvania·
4.5
(9) review
George St., Reading, PA
2
Pennsylvania State Capitol
Harrisburg, Pennsylvania·
4.5
(977) review
Teddy Roosevelt declared that this Italian Renaissance-style building was “the handsomest building I ever saw”. Indeed, the State Capitol, with its vaulted dome and grand staircase and the murals and painted floors inside, is thing to behold.
Third Street ird Street d Street Street reet et, Harrisburg, PA 17101
3
Cathedral of Learning
Pittsburgh, Pennsylvania·
4.5
(979) review
4200 5th Ave., Pittsburgh, PA 15260
4
Point State Park
Pittsburgh, Pennsylvania·
4.5
(951) review
Serving as a key strategic spot during the French and Indian War, this National Historic Landmark and park offer stunning views of the city and a variety of outdoor recreation.
601 Commonwealth Pl Bldg A, Pittsburgh, PA 15222
5
Lock 3
Akron, Ohio·
4.5
(98) review
200 S Main St, Akron, OH 44308-1315
6
Rock & Roll Hall of Fame
Cleveland, Ohio·
4.5
(9964) review
Headquartered in a boldly designed building on Lake Erie's shore, The Rock and Roll Hall of Fame is a 150,000-square-foot museum featuring ever-changing exhibits documenting the history of rock and roll, from Elvis to our days. You’ll see hundreds of original artifacts, from Jimi Hendrix outfits to The Beatles’ handwritten lyrics. Experience the excitement of a Rock Hall induction night at the Power of Rock Experience or have your very own jam session at the Garage. You can also watch a concert while you're here, so check out the Rock Hall’s schedule and plan ahead. – Tripadvisor
1100 Rock and Roll Blvd Main Terminal, Cleveland, OH 44114-1023
7
Allen County War Memorial Coliseum
Fort Wayne, Indiana·
4.0
(99) review
4000 Parnell Ave, Fort Wayne, IN 46805-1414
8
Michigan Avenue Bridge
Chicago, Illinois·
4.5
(985) review
The view from the bridge is one of the best vistas the city has to offer.
333 Michigan Ave, Chicago, IL 60601-3901
9
Boystown
Chicago, Illinois·
4.5
(98) review
Located in Chicago's North Side, this vibrant neighborhood is known for its exciting nightlife and for being one of the largest LGBTQIA+ communities in the city. It's the host of the annual Chicago Pride Parade, and a must-see in the area is the Legacy Walk on Halsted Street, where you can learn about the contributions of the LGBTQIA+ community while admiring the colorful street art and rainbow crosswalks. Check out the unique shops and then grab a bite at one of the area's delicious Thai or Mexican restaurants. At night, visit one of the neighborhood's bars to enjoy a drag show, concert, and tasty cocktail. Consider taking a food or walking tour of Chicago that stops by Boystown. – Tripadvisor
Chicago, IL
10
Wrigley Field
Chicago, Illinois·
4.5
(9953) review
Get a behind-the-scenes look at the legendary home of the Chicago Cubs with Wrigley Field Tours. Built in 1914, this must-see Chicago attraction houses more than 100 years of history. New this year, fans can join us on a non-gameday Ivy Tour which includes the opportunity to take a photo in front of Wrigley Field’s historic ivy wall.
1060 W. Addison St., Chicago, IL 60613-4566
11
Alliant Energy Center
Madison, Wisconsin·
4.0
(99) review
Our premier downtown multi-venue complex features four unique and versatile venues: Veterans Memorial Coliseum, Exhibition Hall, the New Holland Pavilions, and Willow Island. A top choice for expositions, conventions, meetings, concerts, sporting events, ag events, and much more, the Alliant Energy Center complex is a one-stop-shop for all your events. Ample parking, mouthwatering catering, dedicated staff, and a full range of rental equipment & high speed internet make AEC an event planners delight!
1919 Alliant Energy Center Way, Madison, WI 53713-1400
12
First Unitarian Meeting House of Madison
Madison, Wisconsin·
4.5
(96) review
900 University Bay Dr, Madison, WI 53705-2298
13
Stockyards Ag Experience
Sioux Falls, South Dakota·
4.5
(8) review
We deepen the connection between agriculture to everyday life with learning experiences that highlight history, science, culture and economic impact. We educate through interactive displays, hands-on learning and vibrant stories.
301 E Falls Park Dr Main Entrance is on the South side of the building., Sioux Falls, SD 57104-5962
14
Stogeez Cigar Lounge
Sioux Falls, South Dakota·
4.0
(8) review
201 E 11th St, Sioux Falls, SD 57104-6748
15
Little Wine Cellar Co
Sioux Falls, South Dakota·
5.0
(9) review
2390 S Louise Ave, Sioux Falls, SD 57106-4337

CHECKLIST

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FAQ
Frequently Asked Questions
What's the driving distance between Lancaster and Sioux Falls?
The distance is 1,272 miles
What's the travel time between Lancaster and Sioux Falls?
The driving time can vary depending on traffic conditions, but it is typically 23h 27m mins in normal traffic
What are some of the best cities to visit between Lancaster and Sioux Falls?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Sioux Falls?
There are plenty! Here are some stops you shouldn’t miss on your way to Sioux Falls
What’s the weather like in Sioux Falls?
The weather in Sioux Falls is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Sioux Falls in January
Weather in Sioux Falls in February
Weather in Sioux Falls in March
Weather in Sioux Falls in April
Weather in Sioux Falls in May
Weather in Sioux Falls in June
Weather in Sioux Falls in July
Weather in Sioux Falls in August
Weather in Sioux Falls in September
Weather in Sioux Falls in October
Weather in Sioux Falls in November
Weather in Sioux Falls in December
Interested in a detailed plan for your time in Sioux Falls?
Plan your dream Sioux Falls trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Sioux Falls
A 2-day itinerary in Sioux Falls
A 3-day itinerary in Sioux Falls
A 4-day itinerary in Sioux Falls
A 5-day itinerary in Sioux Falls
A 6-day itinerary in Sioux Falls
Where else can I travel to if I'm starting my trip in Lancaster?
We have a lot of great trip options for Lancaster! See the links below for all the itineraries we created for you