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By Huuk Team

Road trip from Knoxville to Lancaster

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Show more (2+)

ITINERARY

10h 51m578 miles20 stops
1
Craggy Mountain Line
111 N Woodfin Ave, Asheville, NC 28804-8818
2
The Mill and Mine
227 W Depot Ave, Knoxville, TN 37917-7521
3
Peter Kern Library
407 Union Ave, Knoxville, TN 37902-2112
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
4
Krutch Park
504 Market St, Knoxville, TN 37902-2107
5
Knoxville Botanical Garden
2743 Wimpole Ave, Knoxville, TN 37914-5958
6
Muse Knoxville
516 N Beaman St, Knoxville, TN 37914-4410
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
7
Cathedral of the Most Sacred Heart of Jesus
711 S Northshore Dr, Knoxville, TN 37919-7593
8
Green Ridge Recreation Center & Splash Valley Water Park
7415 Wood Haven Rd, Roanoke, VA 24019-1901
Designed with family fun in mind, Green Ridge offers two great attractions in one convenient location! The indoor center is open year round, featuring family friendly activities like swimming, interactive games, a gymnasium and fitness area. Splash Valley Water Park is an outdoor aquatics area open Memorial Day to Labor Day, featuring two 34-foot high slides, a sprayground and a current river. Daily admission is available to either facility.
9
A Few Old Goats Brewing
515 8th St Suite 228, Roanoke, VA 24016-3530
10
Virginia Museum of Transportation
303 Norfolk Ave SW, Roanoke, VA 24016-3620
Antique automobiles and trucks, electric and deisel locomotives, and vintage steam, are all part of the nostalgic show at this historic freight station that doubles as a museum .
11
Ladles & Linens Kitchen Shoppe
305 Market St SE, Roanoke, VA 24011-2105
12
Science Museum of Western Virginia & Hopkins Planetarium
1 Market Sq SE 4th Floor, Roanoke, VA 24011-1429
Fun for the whole family, the Science Museum of Western Virginia features a tropical butterfly garden filled with butterflies from around the world; fun and interactive exhibits exploring Healthy Bodies, Healthy Earth and How It Works; live animals and the popular "FROGS"; the Living River & Touch Tank; and amazing traveling exhibits such as "TUTANKHAMUN: Wonderful Things From The Pharaoh's Tomb," running June 14-Dec. 31, 2014.
13
St. Andrew's Roman Catholic Church
631 N Jefferson St, Roanoke, VA 24016-1401
14
Carvins Cove Natural Reserve
9644 Reservoir Rd, Roanoke, VA 24019-7916
15
Howard Peters Rawlings Conservatory and Botanic Gardens of Baltimore
3100 Swann Dr Druid Hill Park, Baltimore, MD 21217
16
Cathedral of Saint Patrick
212 State St, Harrisburg, PA 17101-1108
17
Pennsylvania State Capitol
Third Street ird Street d Street Street reet et, Harrisburg, PA 17101
Teddy Roosevelt declared that this Italian Renaissance-style building was “the handsomest building I ever saw”. Indeed, the State Capitol, with its vaulted dome and grand staircase and the murals and painted floors inside, is thing to behold.
18
Pennsylvania National Fire Museum
1820 N 4th St, Harrisburg, PA 17102-1501
Enter the 1899 Victorian Firehouse, Home of the Reily Hose Co. No. 10 and experience the sights and sounds of Firefighting History. The Pennsylvania National Fire Museum features fire apparatus from Handtubs and Steam Pumpers, hand drawn to horse drawn, to motorized Engines and a 1935 MACK tillered Ladder Truck. An outstanding and varied collection of artifacts are on display
19
Kohl Memorial Park
1050 Downhower Rd., Harrisburg, PA
20
Genesius Theatre
153 N 10th St, Reading, PA 19601-3704
Genesius Theatre is a Performance Venue that specializes in Musical Theatre. The theatre doubles as a learning center for kids by providing 2-3 kids / teen performances and 4-6 week kids summer theatre camp every year. The "Genesius Difference" is the up-close atmosphere of the performances. We trust in the power of this inspiring & dynamic medium to transform the artists who create it, the audiences who enjoy it, and the patrons who support it.
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OVERVIEW

1
Start:Craggy Mountain Line
Asheville, North Carolina·
4.5
(9) review
111 N Woodfin Ave, Asheville, NC 28804-8818
2
The Mill and Mine
Knoxville, Tennessee·
5.0
(9) review
227 W Depot Ave, Knoxville, TN 37917-7521
3
Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
407 Union Ave, Knoxville, TN 37902-2112
4
Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
5
Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
6
Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
516 N Beaman St, Knoxville, TN 37914-4410
7
Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
8
Green Ridge Recreation Center & Splash Valley Water Park
Roanoke, Virginia·
4.0
(73) review
Designed with family fun in mind, Green Ridge offers two great attractions in one convenient location! The indoor center is open year round, featuring family friendly activities like swimming, interactive games, a gymnasium and fitness area. Splash Valley Water Park is an outdoor aquatics area open Memorial Day to Labor Day, featuring two 34-foot high slides, a sprayground and a current river. Daily admission is available to either facility.
7415 Wood Haven Rd, Roanoke, VA 24019-1901
9
A Few Old Goats Brewing
Roanoke, Virginia·
4.5
(9) review
515 8th St Suite 228, Roanoke, VA 24016-3530
10
Virginia Museum of Transportation
Roanoke, Virginia·
4.5
(715) review
Antique automobiles and trucks, electric and deisel locomotives, and vintage steam, are all part of the nostalgic show at this historic freight station that doubles as a museum .
303 Norfolk Ave SW, Roanoke, VA 24016-3620
11
Ladles & Linens Kitchen Shoppe
Roanoke, Virginia·
5.0
(8) review
305 Market St SE, Roanoke, VA 24011-2105
12
Science Museum of Western Virginia & Hopkins Planetarium
Roanoke, Virginia·
4.0
(94) review
Fun for the whole family, the Science Museum of Western Virginia features a tropical butterfly garden filled with butterflies from around the world; fun and interactive exhibits exploring Healthy Bodies, Healthy Earth and How It Works; live animals and the popular "FROGS"; the Living River & Touch Tank; and amazing traveling exhibits such as "TUTANKHAMUN: Wonderful Things From The Pharaoh's Tomb," running June 14-Dec. 31, 2014.
1 Market Sq SE 4th Floor, Roanoke, VA 24011-1429
13
St. Andrew's Roman Catholic Church
Roanoke, Virginia·
4.5
(93) review
631 N Jefferson St, Roanoke, VA 24016-1401
14
Carvins Cove Natural Reserve
Roanoke, Virginia·
4.5
(95) review
9644 Reservoir Rd, Roanoke, VA 24019-7916
15
Howard Peters Rawlings Conservatory and Botanic Gardens of Baltimore
Baltimore, Maryland·
4.5
(99) review
3100 Swann Dr Druid Hill Park, Baltimore, MD 21217
16
Cathedral of Saint Patrick
Harrisburg, Pennsylvania·
4.5
(64) review
212 State St, Harrisburg, PA 17101-1108
17
Pennsylvania State Capitol
Harrisburg, Pennsylvania·
4.5
(977) review
Teddy Roosevelt declared that this Italian Renaissance-style building was “the handsomest building I ever saw”. Indeed, the State Capitol, with its vaulted dome and grand staircase and the murals and painted floors inside, is thing to behold.
Third Street ird Street d Street Street reet et, Harrisburg, PA 17101
18
Pennsylvania National Fire Museum
Harrisburg, Pennsylvania·
5.0
(77) review
Enter the 1899 Victorian Firehouse, Home of the Reily Hose Co. No. 10 and experience the sights and sounds of Firefighting History. The Pennsylvania National Fire Museum features fire apparatus from Handtubs and Steam Pumpers, hand drawn to horse drawn, to motorized Engines and a 1935 MACK tillered Ladder Truck. An outstanding and varied collection of artifacts are on display
1820 N 4th St, Harrisburg, PA 17102-1501
19
Kohl Memorial Park
Harrisburg, Pennsylvania·
5.0
(8) review
1050 Downhower Rd., Harrisburg, PA
20
Genesius Theatre
Reading, Pennsylvania·
4.0
(9) review
Genesius Theatre is a Performance Venue that specializes in Musical Theatre. The theatre doubles as a learning center for kids by providing 2-3 kids / teen performances and 4-6 week kids summer theatre camp every year. The "Genesius Difference" is the up-close atmosphere of the performances. We trust in the power of this inspiring & dynamic medium to transform the artists who create it, the audiences who enjoy it, and the patrons who support it.
153 N 10th St, Reading, PA 19601-3704

CHECKLIST

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FAQ
Frequently Asked Questions
What's the driving distance between Knoxville and Lancaster?
The distance is 578 miles
What's the travel time between Knoxville and Lancaster?
The driving time can vary depending on traffic conditions, but it is typically 10h 51m mins in normal traffic
What are some of the best cities to visit between Knoxville and Lancaster?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Lancaster?
There are plenty! Here are some stops you shouldn’t miss on your way to Lancaster
What’s the weather like in Lancaster?
The weather in Lancaster is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Lancaster in January
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Interested in a detailed plan for your time in Lancaster?
Plan your dream Lancaster trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Lancaster
A 2-day itinerary in Lancaster
A 3-day itinerary in Lancaster
A 4-day itinerary in Lancaster
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Where else can I travel to if I'm starting my trip in Knoxville?
We have a lot of great trip options for Knoxville! See the links below for all the itineraries we created for you