Road trip from Knoxville to Greenville
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Fun & Games
Museums
Classes & Workshops
Outdoor Activities
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Sights & Landmarks
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All Category
Fun & Games
Museums
Classes & Workshops
Outdoor Activities
Spas & Wellness
Sights & Landmarks
Food & Drink
Nightlife
Nature & Parks
Concerts & Shows
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ITINERARY
3h 38m171 miles28 stops
1
Knoxville National Cemetery
2
The Mill and Mine
3
PostModern Spirits
PostModern Spirits in the heart of Knoxville's Old City open 7 days a week produces mindfully crafted spirits for the modern drinker. Visitors can savor PostModern's various offerings in the comfortable cocktail/tasting room or Thursday-Sunday join one of the fun distillery tours and tastings. Now producing several distinct varieties of gin, vodka, liqueurs like chamomile, cacao, elderberry, and bitter orange amaro arancia. Along with our American Single Malt Whiskey developed in collaboration with a local brewery!
4
Peter Kern Library
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
5
Krutch Park
6
Knoxville Botanical Garden
7
Muse Knoxville
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
8
Cathedral of the Most Sacred Heart of Jesus
9
Radius Rooftop Lounge
10
Farragut Folklife Museum
11
Grove Arcade
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
12
Asheville Museum of Science
The Asheville Museum of Science (AMOS) is Western North Carolina’s home for experiential science learning, discovery, and exploration. AMOS strives to spark the imagination and foster lifelong curiosity. We have plenty of science to come and explore including the Colburn Hall of Minerals, STEM lab, interactive panorama screen, Teratophoneus dinosaur skeleton and fossil dig, Southern Appalachian Forest tree climb, Terrabox elevation simulator, Toddler Nest, fun temporary exhibits, and museum store.
13
Lexington Glassworks
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
14
Green Man Brewery
The Legendary Green Man has existed for centuries but it’s no myth that he’s been brewing great beer in Asheville since 1997. As home to one of North Carolina’s oldest breweries, tasting rooms and sour programs, Green Man has been producing some of the beer scene’s most iconic ales for many years. We are consistently recognized for our internationally loved traditional English styles and creative versions of the newest craft trends. Our brewers strive to bring innovative and exciting new flavors to all beer-loving folks. From Asheville’s first tasting room to one of Downtown Asheville’s largest tasting rooms, our storied growth has brought us to 2 brew houses, 3 tasting rooms, and 2 buildings. Our newest facility in Asheville’s South Slope Neighborhood is a 3 story, 22,000 sqft. packaging hall and specialty brewhouse including a “brewtique” and an indoor/outdoor taproom loft overlooking the Blue Ridge Mountains. When you visit, make sure to visit the original tasting room next door.
15
French Broad River Brewery
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
16
Still Point Wellness Spa
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
17
Wolverine Paintball Park
18
Tarheel Lanes
19
Apple Valley Model Railroad Club
Largest model railroad in western North Carolina housed in the historic 1902 train depot in Hendersonville, NC. A 100' X 20' HO scale model railroad based on western North Carolina in the mid 1900s fills most of the depot and a real caboose sits just outside. Artifacts from real railroads are on display throughout the depot. The club has a 60' X 12' outdoor G scale layout that is very popular. Inside, there is also a separate Thomas the Tank train layout for young engineers to operate, a telegraph and an old engine name Pauline. For those interested, we also offer a scavenger hunt. Just ask one of us for a copy. The Apple Valley Model Railroad is open to the public Wednesdays 1 to 3 and Saturdays 10 to 2. Admission is free, and donations are greatly appreciated.
20
Point Lookout Vineyards
21
Frank's Gentlemen's Salon
22
Sassy Paints
Sassy Paints is a BYOB art studio, offering 2 and 3 hour classes in the evenings. We have kids art classes and we are available private birthday parties and special events!
23
Shoeless Joe Jackson Museum and Baseball Library
The Shoeless Joe Jackson Museum and Baseball Library is an independent, non-profit organization located in the former home of Joe and his wife, Katie. We are dedicated to honoring the life and preserving the legacy of the greatest natural hitter to ever play the game. Through the research, collection, and display of many original artifacts, photos, and countless books in our on-site research library, we provide comprehensive context for Joe's place in baseball history. In addition to dispelling myths and educating the public about the truth of Joe's life and career, our mission is to be an active, contributing member within our local communities, continuing to grow the game of baseball for generations to come.
24
Greenville Zoo
25
Roper Mountain Science Center
Roper Mountain Science Center’s mission is to ignite the natural curiosity of all learners to explore and shape their world. Located just off of I-385 at Roper Mountain Road, Roper Mountain contains an array of state-of-the-art educational facilities on its 62-acre campus. Visitors experience the latest in STEM education through interactive exhibits and several hands-on activities. Families can attend numerous events throughout the year including Friday Starry Nights, Summer Adventure and Afterschool Explorations. Roper Mountain provides the opportunity to explore, imagine and grow as a learner of any age. Roper Mountain Science Center is only open to the public for select events throughout the yearFor more information, visit RoperMountain.org.
26
Speed Factory Indoor Karting
Located at 1524 Roper Mountain Rd, Speed Factory is Greenville's only high speed indoor go kart track. Racers will create a racing profile to track their scores, then head on track for a 35mph indoor kart racing experience like no other. Open all year long, the indoor track is the perfect spot for fun!
27
West Main Artists Co-Op
28
Oakwood Cemetary
Customize this Trip
OVERVIEW
1
Start:Knoxville National Cemetery
Knoxville, Tennessee·
5.0
(9) review
939 Tyson St, Knoxville, TN 37917-7143
2
Start:The Mill and Mine
Knoxville, Tennessee·
5.0
(9) review
227 W Depot Ave, Knoxville, TN 37917-7521
3
Start:PostModern Spirits
Knoxville, Tennessee·
5.0
(9) review
PostModern Spirits in the heart of Knoxville's Old City open 7 days a week produces mindfully crafted spirits for the modern drinker. Visitors can savor PostModern's various offerings in the comfortable cocktail/tasting room or Thursday-Sunday join one of the fun distillery tours and tastings. Now producing several distinct varieties of gin, vodka, liqueurs like chamomile, cacao, elderberry, and bitter orange amaro arancia. Along with our American Single Malt Whiskey developed in collaboration with a local brewery!
4
Start:Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
5
Start:Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
6
Start:Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
7
Start:Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
8
Start:Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
9
Start:Radius Rooftop Lounge
Knoxville, Tennessee·
4.0
(9) review
Embassy Suites By Hilton 507 S Gay St, Knoxville, TN 37902
10
Start:Farragut Folklife Museum
Knoxville, Tennessee·
4.5
(9) review
11408 Municipal Center Dr, Knoxville, TN 37934-2830
11
Start:Grove Arcade
Asheville, North Carolina·
4.0
(987) review
Grove Arcade is a beautifully preserved historical building in the heart of Downtown Asheville that represents the heart and character of the town. It’s rich history and ornate architecture combined with its eclectic mix of shops and restaurants offer patrons a full-day immersion into Asheville lifestyle and culture.
12
Start:Asheville Museum of Science
Asheville, North Carolina·
3.5
(96) review
The Asheville Museum of Science (AMOS) is Western North Carolina’s home for experiential science learning, discovery, and exploration. AMOS strives to spark the imagination and foster lifelong curiosity. We have plenty of science to come and explore including the Colburn Hall of Minerals, STEM lab, interactive panorama screen, Teratophoneus dinosaur skeleton and fossil dig, Southern Appalachian Forest tree climb, Terrabox elevation simulator, Toddler Nest, fun temporary exhibits, and museum store.
13
Start:Lexington Glassworks
Asheville, North Carolina·
4.5
(983) review
Lexington Glassworks, located in the heart of downtown Asheville, NC, was born out of the desire to create timeless and innovative hand-blown glass. Each piece is skillfully crafted using century-old techniques with the singular goal of creating top-notch work. The gallery features high-quality custom lighting and handmade glass for any budget. Lexington Glassworks is a makers studio where the public is invited to view the artists at work.
14
Start:Green Man Brewery
Asheville, North Carolina·
4.5
(96) review
The Legendary Green Man has existed for centuries but it’s no myth that he’s been brewing great beer in Asheville since 1997. As home to one of North Carolina’s oldest breweries, tasting rooms and sour programs, Green Man has been producing some of the beer scene’s most iconic ales for many years. We are consistently recognized for our internationally loved traditional English styles and creative versions of the newest craft trends. Our brewers strive to bring innovative and exciting new flavors to all beer-loving folks. From Asheville’s first tasting room to one of Downtown Asheville’s largest tasting rooms, our storied growth has brought us to 2 brew houses, 3 tasting rooms, and 2 buildings. Our newest facility in Asheville’s South Slope Neighborhood is a 3 story, 22,000 sqft. packaging hall and specialty brewhouse including a “brewtique” and an indoor/outdoor taproom loft overlooking the Blue Ridge Mountains. When you visit, make sure to visit the original tasting room next door.
15
Start:French Broad River Brewery
Asheville, North Carolina·
4.0
(98) review
We are open with a limited indoor capacity and plenty of spaced tables outside and inside. We thank you for following our mask and social distancing taproom rules and can’t wait to pour you some pint! Original Papa Nicks Pizza & Restaurant is open Weds-Sunday. We have Food Trucks on Monday and Tuesdays. Cheers! We have been brewing quality craft beer in the heart of Asheville, North Carolina since 2001. Our large new taproom is family friendly, We have games, ping pong, foosball and many large TVs to watch sports and events. We have food available everyday from Original Papa Nicks, Full menu which includes Traditional pizza and more! Menu is dietary restriction friendly and available for take out and catering. We are conveniently located at the edge of Biltmore Village, between Sweeten Creek and Fairview Road. See you soon, Cheers!
16
Start:Still Point Wellness Spa
Asheville, North Carolina·
5.0
(968) review
Still Point Wellness offers a carefully curated menu of world-class services to support personal development through deep relaxation and self exploration. Unique modalities include Salt Water Floatation, Esalen Massage, Craniosacral Therapy and Somatic Experiencing.
17
Start:Wolverine Paintball Park
Hendersonville, North Carolina·
4.5
(10) review
487 Brookside Camp Rd, Hendersonville, NC 28792-1116
18
Start:Tarheel Lanes
Hendersonville, North Carolina·
3.0
(9) review
3275 Asheville Hwy, Hendersonville, NC 28791-1050
19
Start:Apple Valley Model Railroad Club
Hendersonville, North Carolina·
5.0
(87) review
Largest model railroad in western North Carolina housed in the historic 1902 train depot in Hendersonville, NC. A 100' X 20' HO scale model railroad based on western North Carolina in the mid 1900s fills most of the depot and a real caboose sits just outside. Artifacts from real railroads are on display throughout the depot. The club has a 60' X 12' outdoor G scale layout that is very popular. Inside, there is also a separate Thomas the Tank train layout for young engineers to operate, a telegraph and an old engine name Pauline. For those interested, we also offer a scavenger hunt. Just ask one of us for a copy. The Apple Valley Model Railroad is open to the public Wednesdays 1 to 3 and Saturdays 10 to 2. Admission is free, and donations are greatly appreciated.
20
Start:Point Lookout Vineyards
Hendersonville, North Carolina·
4.5
(89) review
408 Appleola Road, Hendersonville, NC 28792
21
Start:Frank's Gentlemen's Salon
Greenville, South Carolina·
5.0
(8) review
5A E Coffee St, Greenville, SC 29601-2704
22
Start:Sassy Paints
Greenville, South Carolina·
5.0
(9) review
Sassy Paints is a BYOB art studio, offering 2 and 3 hour classes in the evenings. We have kids art classes and we are available private birthday parties and special events!
23
Start:Shoeless Joe Jackson Museum and Baseball Library
Greenville, South Carolina·
4.5
(85) review
The Shoeless Joe Jackson Museum and Baseball Library is an independent, non-profit organization located in the former home of Joe and his wife, Katie. We are dedicated to honoring the life and preserving the legacy of the greatest natural hitter to ever play the game. Through the research, collection, and display of many original artifacts, photos, and countless books in our on-site research library, we provide comprehensive context for Joe's place in baseball history. In addition to dispelling myths and educating the public about the truth of Joe's life and career, our mission is to be an active, contributing member within our local communities, continuing to grow the game of baseball for generations to come.
24
Start:Greenville Zoo
Greenville, South Carolina·
4.0
(996) review
150 Cleveland Park Dr, Greenville, SC 29601-3147
25
Start:Roper Mountain Science Center
Greenville, South Carolina·
4.5
(90) review
Roper Mountain Science Center’s mission is to ignite the natural curiosity of all learners to explore and shape their world. Located just off of I-385 at Roper Mountain Road, Roper Mountain contains an array of state-of-the-art educational facilities on its 62-acre campus. Visitors experience the latest in STEM education through interactive exhibits and several hands-on activities. Families can attend numerous events throughout the year including Friday Starry Nights, Summer Adventure and Afterschool Explorations. Roper Mountain provides the opportunity to explore, imagine and grow as a learner of any age. Roper Mountain Science Center is only open to the public for select events throughout the yearFor more information, visit RoperMountain.org.
26
Start:Speed Factory Indoor Karting
Greenville, South Carolina·
4.5
(8) review
Located at 1524 Roper Mountain Rd, Speed Factory is Greenville's only high speed indoor go kart track. Racers will create a racing profile to track their scores, then head on track for a 35mph indoor kart racing experience like no other. Open all year long, the indoor track is the perfect spot for fun!
27
Start:West Main Artists Co-Op
Spartanburg, South Carolina·
5.0
(9) review
578 W Main St, Spartanburg, SC 29301-2162
28
Start:Oakwood Cemetary
Spartanburg, South Carolina·
4.5
(9) review
182 Oakwood Ave, Spartanburg, SC 29302-1602
CHECKLIST
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Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
Camera or smartphone
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FAQ
Frequently Asked Questions
What's the driving distance between Knoxville and Greenville?
The distance is 171 miles
What's the travel time between Knoxville and Greenville?
The driving time can vary depending on traffic conditions, but it is typically 3h 38m mins in normal traffic
What are some of the best cities to visit between Knoxville and Greenville?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Greenville?
There are plenty! Here are some stops you shouldn’t miss on your way to Greenville
What’s the weather like in Greenville?
The weather in Greenville is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Greenville in January
Weather in Greenville in February
Weather in Greenville in March
Weather in Greenville in April
Weather in Greenville in May
Weather in Greenville in June
Weather in Greenville in July
Weather in Greenville in August
Weather in Greenville in September
Weather in Greenville in October
Weather in Greenville in November
Weather in Greenville in December
Interested in a detailed plan for your time in Greenville?
Plan your dream Greenville trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Greenville
A 2-day itinerary in Greenville
A 3-day itinerary in Greenville
A 4-day itinerary in Greenville
A 5-day itinerary in Greenville
A 6-day itinerary in Greenville
Where else can I travel to if I'm starting my trip in Knoxville?
We have a lot of great trip options for Knoxville! See the links below for all the itineraries we created for you