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By Huuk Team

Road trip from Huntsville to Winston-Salem

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Show more (5+)

ITINERARY

9h 4m480 miles24 stops
1
Huntsville Botanical Garden
4747 Bob Wallace Ave SW, Huntsville, AL 35805-3390
The 118-acre Huntsville Botanical Garden is open year-round and contains a diverse ecosystem of meadows, upland and bottomland forest, and wetlands, as well as a variety of specialty gardens and native plant collections. The Mathews Nature Trail contains the largest accredited trillium collection in the U.S. and the Anderson Education Center is home to the nation’s largest open-air butterfly house. The Native Plants Teaching Garden is a public space that highlights the way local plants, soil, pollinators, and birds create distinct communities and how they interact to form a diverse, sustainable, and attractive landscape. A 501(c)(3) non-profit organization, the Garden is a member of the American Public Gardens Association, the North American Plant Collections Consortium, and the American Horticultural Society, as well as an ArbNet-accredited arboretum.
2
The Cigar Box Guitar Store
2211 Seminole Dr SW Studio 106, Huntsville, AL 35805-3848
The only one in the world! The Cigar Box Guitar Store located in Studio 106 at Lowe Mill A&E features art you can touch. There are dozens of handmade three-and-four string cigar box guitars and other cigar box instruments that visitors can play. Learn more about how these unique instruments are created by the artist himself most Friday and Saturday afternoons. Want to learn how to play cigar box guitar? Come for free lessons on Saturdays anytime between Noon-2:00 and borrow a guitar.
3
The Deep Comics & Games
2205 Mock Road SW Huntsville, AL, Huntsville, AL 35801
One of the largest comic / games / toys stores in the South East! Board Games and TCG Games daily!
4
Church Street Wine Shoppe
501 Church St NW, Huntsville, AL 35801-5507
A premier retail and wine shoppe, serving specialty beers and tapas as well. We offer a large variety of wines, delicious food selections, and even gift baskets & gift cards!
5
Earlyworks Museum Complex
404 Madison St SE, Huntsville, AL 35801-4203
Interactive children's museum focused on teaching about Alabama history.
6
River Gallery
400 E 2nd St, Chattanooga, TN 37403-1105
Craft and art collections.
7
Chattanooga Zoo
301 N Holtzclaw Ave Warner Park, Chattanooga, TN 37404-2306
Imagine a zoo that's specially designed to bring the animals up close to you. Imagine a zoo where you have time to notice the subtleties of animal behavior, instead of being pushed along by an impatient crowd. Imagine an exciting and diverse zoo that's still easy to navigate with strollers...or little legs. That's the new Chattanooga Zoo!
8
The Spice & Tea Exchange of Chattanooga
2115 Gunbarrel Rd Suite A-13, Chattanooga, TN 37421-2674
Come In and Smell the Spices! The Spice & Tea Exchange® offers food lovers, chefs, and tea enthusiasts a unique shopping experience filled with culinary delights. Explore your inner chef and shop over 140 fine spices, 75+ hand-mixed seasoning blends, sugars, salts, loose-leaf teas, and accessories. Create your own gourmet gift, or choose from a variety of gift boxes and recipe samplers!
9
Cathedral of the Most Sacred Heart of Jesus
711 S Northshore Dr, Knoxville, TN 37919-7593
10
Peter Kern Library
407 Union Ave, Knoxville, TN 37902-2112
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
11
Krutch Park
504 Market St, Knoxville, TN 37902-2107
12
Knoxville Botanical Garden
2743 Wimpole Ave, Knoxville, TN 37914-5958
13
Craggy Mountain Line
111 N Woodfin Ave, Asheville, NC 28804-8818
14
Muse Knoxville
516 N Beaman St, Knoxville, TN 37914-4410
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
15
Iron Heart Winery
3742 Boone Furnace Rd, Allisonia, VA 24347-4001
16
JDL Fast Track
2505 Empire Dr, Winston Salem, NC 27103-6709
17
Historic Bethania, NC
5393 Ham Horton Lane Bethania, NC, Winston Salem, NC 27010
18
Hanes Mall
3320 Silas Creek Pkwy, Winston Salem, NC 27103-3031
Hanes Mall features favorite stores such as Belk, Dillard's, Macy's, JCPenney, Sears, and Old Navy as well as specialty shops like American Eagle, Abercrombie & Fitch, Gymboree and Banana Republic.
19
European Touch
116 Reynolda Vlg, Winston Salem, NC 27106-5123
20
Reynolda House Museum of American Art
2250 Reynolda Rd, Winston Salem, NC 27106-5117
Nestled within 180 acres adjacent to Wake Forest University, Reynolda is the perfect place to escape and discover art, nature, history, and so much more. View Reynolda’s world-renowned American art collection and curated exhibitions on display throughout the interiors of Katharine and R.J. Reynolds’s 1917 bungalow and in the Babcock Gallery. Plus, learn about the Reynolds family, Katharine’s vision, and the history of the estate. After touring the Museum, embrace the outdoors in the Gardens and grounds, which are always free and open to the public year-round from sunrise to sunset. Do flowers make you hungry? Make your way to Reynolda Village to shop and dine.
21
Lam Museum of Anthropology, Wake Forest University
Palmer Hall, Carroll Weathers Drive, Winston Salem, NC 27109
Discover North Carolina's only museum dedicated to the study of global cultures. Explore stories of humanity, from ancient archaeological sites to the celebrations and struggles of today. Learn about peoples around the world through their everyday and ceremonial objects, and visual arts. Changing exhibits highlight the Museum's collections of nearly 30,000 archaeological and ethnographic artifacts from more than 350 cultures and 90 countries. Admission is free.
22
Grand 18-Winston-Salem
5601 University Pkwy, Winston Salem, NC 27105-1313
23
Recreation Billiards
412 W 4th St, Winston Salem, NC 27101-2805
24
Salem Lake
1001 Salem Lake Rd, Winston Salem, NC 27107-1571
Customize this Trip

OVERVIEW

1
Start:Huntsville Botanical Garden
Huntsville, Alabama·
4.5
(912) review
The 118-acre Huntsville Botanical Garden is open year-round and contains a diverse ecosystem of meadows, upland and bottomland forest, and wetlands, as well as a variety of specialty gardens and native plant collections. The Mathews Nature Trail contains the largest accredited trillium collection in the U.S. and the Anderson Education Center is home to the nation’s largest open-air butterfly house. The Native Plants Teaching Garden is a public space that highlights the way local plants, soil, pollinators, and birds create distinct communities and how they interact to form a diverse, sustainable, and attractive landscape. A 501(c)(3) non-profit organization, the Garden is a member of the American Public Gardens Association, the North American Plant Collections Consortium, and the American Horticultural Society, as well as an ArbNet-accredited arboretum.
4747 Bob Wallace Ave SW, Huntsville, AL 35805-3390
2
The Cigar Box Guitar Store
Huntsville, Alabama·
5.0
(9) review
The only one in the world! The Cigar Box Guitar Store located in Studio 106 at Lowe Mill A&E features art you can touch. There are dozens of handmade three-and-four string cigar box guitars and other cigar box instruments that visitors can play. Learn more about how these unique instruments are created by the artist himself most Friday and Saturday afternoons. Want to learn how to play cigar box guitar? Come for free lessons on Saturdays anytime between Noon-2:00 and borrow a guitar.
2211 Seminole Dr SW Studio 106, Huntsville, AL 35805-3848
3
The Deep Comics & Games
Huntsville, Alabama·
4.5
(9) review
One of the largest comic / games / toys stores in the South East! Board Games and TCG Games daily!
2205 Mock Road SW Huntsville, AL, Huntsville, AL 35801
4
Church Street Wine Shoppe
Huntsville, Alabama·
4.5
(9) review
A premier retail and wine shoppe, serving specialty beers and tapas as well. We offer a large variety of wines, delicious food selections, and even gift baskets & gift cards!
501 Church St NW, Huntsville, AL 35801-5507
5
Earlyworks Museum Complex
Huntsville, Alabama·
4.0
(92) review
Interactive children's museum focused on teaching about Alabama history.
404 Madison St SE, Huntsville, AL 35801-4203
6
River Gallery
Chattanooga, Tennessee·
4.5
(98) review
Craft and art collections.
400 E 2nd St, Chattanooga, TN 37403-1105
7
Chattanooga Zoo
Chattanooga, Tennessee·
4.0
(907) review
Imagine a zoo that's specially designed to bring the animals up close to you. Imagine a zoo where you have time to notice the subtleties of animal behavior, instead of being pushed along by an impatient crowd. Imagine an exciting and diverse zoo that's still easy to navigate with strollers...or little legs. That's the new Chattanooga Zoo!
301 N Holtzclaw Ave Warner Park, Chattanooga, TN 37404-2306
8
The Spice & Tea Exchange of Chattanooga
Chattanooga, Tennessee·
5.0
(92) review
Come In and Smell the Spices! The Spice & Tea Exchange® offers food lovers, chefs, and tea enthusiasts a unique shopping experience filled with culinary delights. Explore your inner chef and shop over 140 fine spices, 75+ hand-mixed seasoning blends, sugars, salts, loose-leaf teas, and accessories. Create your own gourmet gift, or choose from a variety of gift boxes and recipe samplers!
2115 Gunbarrel Rd Suite A-13, Chattanooga, TN 37421-2674
9
Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593
10
Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
407 Union Ave, Knoxville, TN 37902-2112
11
Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
12
Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
13
Craggy Mountain Line
Asheville, North Carolina·
4.5
(9) review
111 N Woodfin Ave, Asheville, NC 28804-8818
14
Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
516 N Beaman St, Knoxville, TN 37914-4410
15
Iron Heart Winery
Allisonia, Virginia·
4.0
(7) review
3742 Boone Furnace Rd, Allisonia, VA 24347-4001
16
JDL Fast Track
Winston Salem, North Carolina·
4.0
(9) review
2505 Empire Dr, Winston Salem, NC 27103-6709
17
Historic Bethania, NC
Winston Salem, North Carolina·
4.0
(46) review
5393 Ham Horton Lane Bethania, NC, Winston Salem, NC 27010
18
Hanes Mall
Winston Salem, North Carolina·
4.0
(85) review
Hanes Mall features favorite stores such as Belk, Dillard's, Macy's, JCPenney, Sears, and Old Navy as well as specialty shops like American Eagle, Abercrombie & Fitch, Gymboree and Banana Republic.
3320 Silas Creek Pkwy, Winston Salem, NC 27103-3031
19
European Touch
Winston Salem, North Carolina·
5.0
(5) review
116 Reynolda Vlg, Winston Salem, NC 27106-5123
20
Reynolda House Museum of American Art
Winston Salem, North Carolina·
4.5
(659) review
Nestled within 180 acres adjacent to Wake Forest University, Reynolda is the perfect place to escape and discover art, nature, history, and so much more. View Reynolda’s world-renowned American art collection and curated exhibitions on display throughout the interiors of Katharine and R.J. Reynolds’s 1917 bungalow and in the Babcock Gallery. Plus, learn about the Reynolds family, Katharine’s vision, and the history of the estate. After touring the Museum, embrace the outdoors in the Gardens and grounds, which are always free and open to the public year-round from sunrise to sunset. Do flowers make you hungry? Make your way to Reynolda Village to shop and dine.
2250 Reynolda Rd, Winston Salem, NC 27106-5117
21
Lam Museum of Anthropology, Wake Forest University
Winston Salem, North Carolina·
4.0
(9) review
Discover North Carolina's only museum dedicated to the study of global cultures. Explore stories of humanity, from ancient archaeological sites to the celebrations and struggles of today. Learn about peoples around the world through their everyday and ceremonial objects, and visual arts. Changing exhibits highlight the Museum's collections of nearly 30,000 archaeological and ethnographic artifacts from more than 350 cultures and 90 countries. Admission is free.
Palmer Hall, Carroll Weathers Drive, Winston Salem, NC 27109
22
Grand 18-Winston-Salem
Winston Salem, North Carolina·
4.0
(72) review
5601 University Pkwy, Winston Salem, NC 27105-1313
23
Recreation Billiards
Winston Salem, North Carolina·
4.0
(9) review
412 W 4th St, Winston Salem, NC 27101-2805
24
Salem Lake
Winston Salem, North Carolina·
4.5
(97) review
1001 Salem Lake Rd, Winston Salem, NC 27107-1571

CHECKLIST

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FAQ
Frequently Asked Questions
What's the driving distance between Huntsville and Winston-Salem?
The distance is 480 miles
What's the travel time between Huntsville and Winston-Salem?
The driving time can vary depending on traffic conditions, but it is typically 9h 4m mins in normal traffic
What are some of the best cities to visit between Huntsville and Winston-Salem?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Winston-Salem?
There are plenty! Here are some stops you shouldn’t miss on your way to Winston-Salem
What’s the weather like in Winston-Salem?
The weather in Winston-Salem is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Winston-Salem in January
Weather in Winston-Salem in February
Weather in Winston-Salem in March
Weather in Winston-Salem in April
Weather in Winston-Salem in May
Weather in Winston-Salem in June
Weather in Winston-Salem in July
Weather in Winston-Salem in August
Weather in Winston-Salem in September
Weather in Winston-Salem in October
Weather in Winston-Salem in November
Weather in Winston-Salem in December
Interested in a detailed plan for your time in Winston-Salem?
Plan your dream Winston-Salem trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Winston-Salem
A 2-day itinerary in Winston-Salem
A 3-day itinerary in Winston-Salem
A 4-day itinerary in Winston-Salem
A 5-day itinerary in Winston-Salem
A 6-day itinerary in Winston-Salem
Where else can I travel to if I'm starting my trip in Huntsville?
We have a lot of great trip options for Huntsville! See the links below for all the itineraries we created for you