Road trip from Houston to Knoxville
All Category
Museums
Nature & Parks
Concerts & Shows
Food & Drink
Spas & Wellness
Casinos & Gambling
Fun & Games
Show more (5+)
All Category
Museums
Nature & Parks
Concerts & Shows
Food & Drink
Spas & Wellness
Casinos & Gambling
Fun & Games
Sights & Landmarks
Shopping
Zoos & Aquariums
Nightlife
Reset
Show less
ITINERARY
16h 58m923 miles17 stops
1
Houston Grand Opera
Opera house in Houston that features opera presentations throughout the year.
2
The Menil Collection
Houston philanthropists and art patrons John and Dominique de Menil established the Menil Foundation in 1954 to foster greater public understanding and appreciation of art, architecture, culture, religion, and philosophy. In 1987, the Menil Collection’s main museum building opened to the public. Today, the Menil Collection consists of a group of five art buildings and green spaces located within a residential neighborhood. The Menil remains committed to its founders’ belief that art is essential to human experience and fosters direct personal encounters with works of art. The museum welcomes all visitors free of charge to its buildings and surrounding green spaces.
3
Lillie and Hugh Roy Cullen Sculpture Garden
4
Reliant Park
5
Space Center Houston
Located in the heart of NASA’s spaceflight program, Space Center Houston is a must-visit for fans of space exploration. With more than 400 space-related artefacts and numerous interactive exhibitions, you can easily spend a whole day learning about NASA’s history and current work. Be sure to hop on the tram tour too, which takes you around the real site of the Johnson Space Center, including the original Mission Control room and a behind-the-scenes look at the astronaut training facilities. You might want to join VIP tours by NASA experts to gain a deeper understanding and inside knowledge of the center. – Tripadvisor
6
Lafayette Science Museum
Step into the vibrant world of the University of Louisiana at Lafayette Science Museum, where curiosity knows no bounds!
7
New Orleans School of Cooking
We teach the basics of Louisiana Cooking in a way you’ll never forget. Fun is a primary ingredient in our kitchen! Our Cajun / Creole experts teach New Orleans specialties such as Gumbo, Jambalaya and Pralines, seasoning them with history, trivia and tall tales! We offer demonstration classes and hands-on classes daily! DEMONSTRATION CLASS: Watch, learn & eat! Sit back and enjoy watching our skilled, entertaining chefs prepare a classic Cajun / Creole meal for you while learning about the vibrant history of New Orleans cuisine - enjoy all the demonstrated items, as well as local Abita beer with your meal! HANDS ON CLASS: Cook & eat an authentic Louisiana meal! In this highly interactive class, our guests prepare a complete dinner with one of our expert chefs, and afterwards they are able to sit down and enjoy the meal they have just created. Served with red & white wine.
8
Jean Lafitte National Historical Park and Preserve
Nature reserve, consisting of several sections, preserves significant examples of the natural and cultural resources of the Mississippi Delta region.
9
The Presbytere
The Presbytere was designed in 1791 to match the Cabildo, alongside St. Louis Cathedral in the French Quarter. It stands today as a beautiful reminder of both Louisiana's singular past and its vibrant present.The Presbytere, originally called Casa Curial or "Ecclesiastical House," was built on the site of the residence, or presbytere, of the Capuchin monks. The building was used for commercial purposes until 1834 when it became a courthouse. In 1911, it became part of the Louisiana State Museum. Two exhibitions are on display-"Living with Hurricanes: Katrina and Beyond" tells of rescue, rebuilding and renewal, and "Mardi Gras: It's Carnival Time in Louisiana" captures the fun and fantasy of the annual celebration.
10
Palm Court Jazz Cafe
A stylish jazz spot in the French Quarter, which serves Cajun and Creole dishes.
11
McWane Science Center
Fun and learning never end at McWane Science Center, a nonprofit, hands-on museum and IMAX(R) Dome Theater. Four floors of interactive exhibits celebrate science and wonder - from an amazing collection of dinosaurs to innovative environmental showcases, imaginative early childhood playgrounds, and an awe-inspiring aquarium. The energy and excitement of discovery spring to life through an extensive lineup of science demonstrations performed daily by talented educators. The adventure intensifies in the IMAX(R) Dome Theater, where wide-eyed visitors experience the sights and sounds of breathtaking films on a 5-story-tall screen surrounded by 3 tons of high-intensity speakers.
12
Statue of Liberty Replica
Bronze replica measuring one-fifth the size of its sister statue located in New York City.
13
River Gallery
Craft and art collections.
14
Chattanooga Zoo
Imagine a zoo that's specially designed to bring the animals up close to you. Imagine a zoo where you have time to notice the subtleties of animal behavior, instead of being pushed along by an impatient crowd. Imagine an exciting and diverse zoo that's still easy to navigate with strollers...or little legs. That's the new Chattanooga Zoo!
15
The Spice & Tea Exchange of Chattanooga
Come In and Smell the Spices! The Spice & Tea Exchange® offers food lovers, chefs, and tea enthusiasts a unique shopping experience filled with culinary delights. Explore your inner chef and shop over 140 fine spices, 75+ hand-mixed seasoning blends, sugars, salts, loose-leaf teas, and accessories. Create your own gourmet gift, or choose from a variety of gift boxes and recipe samplers!
16
Peter Kern Library
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
17
Knoxville Botanical Garden
Customize this Trip
OVERVIEW
1
Start:Houston Grand Opera
Houston, Texas·
4.5
(94) review
Opera house in Houston that features opera presentations throughout the year.
2
Start:The Menil Collection
Houston, Texas·
4.5
(970) review
Houston philanthropists and art patrons John and Dominique de Menil established the Menil Foundation in 1954 to foster greater public understanding and appreciation of art, architecture, culture, religion, and philosophy. In 1987, the Menil Collection’s main museum building opened to the public. Today, the Menil Collection consists of a group of five art buildings and green spaces located within a residential neighborhood. The Menil remains committed to its founders’ belief that art is essential to human experience and fosters direct personal encounters with works of art. The museum welcomes all visitors free of charge to its buildings and surrounding green spaces.
3
Start:Lillie and Hugh Roy Cullen Sculpture Garden
Houston, Texas·
4.5
(96) review
900 Bissonnet St, Houston, TX 77005
4
Start:Reliant Park
Houston, Texas·
4.0
(99) review
1 Nrg Park, Houston, TX 77054-1574
5
Start:Space Center Houston
Houston, Texas·
4.5
(9889) review
Located in the heart of NASA’s spaceflight program, Space Center Houston is a must-visit for fans of space exploration. With more than 400 space-related artefacts and numerous interactive exhibitions, you can easily spend a whole day learning about NASA’s history and current work. Be sure to hop on the tram tour too, which takes you around the real site of the Johnson Space Center, including the original Mission Control room and a behind-the-scenes look at the astronaut training facilities. You might want to join VIP tours by NASA experts to gain a deeper understanding and inside knowledge of the center. – Tripadvisor
6
Start:Lafayette Science Museum
Lafayette, Lafayette Parish, Louisiana·
4.5
(96) review
Step into the vibrant world of the University of Louisiana at Lafayette Science Museum, where curiosity knows no bounds!
7
Start:New Orleans School of Cooking
New Orleans, Louisiana·
5.0
(9878) review
We teach the basics of Louisiana Cooking in a way you’ll never forget. Fun is a primary ingredient in our kitchen! Our Cajun / Creole experts teach New Orleans specialties such as Gumbo, Jambalaya and Pralines, seasoning them with history, trivia and tall tales! We offer demonstration classes and hands-on classes daily! DEMONSTRATION CLASS: Watch, learn & eat! Sit back and enjoy watching our skilled, entertaining chefs prepare a classic Cajun / Creole meal for you while learning about the vibrant history of New Orleans cuisine - enjoy all the demonstrated items, as well as local Abita beer with your meal! HANDS ON CLASS: Cook & eat an authentic Louisiana meal! In this highly interactive class, our guests prepare a complete dinner with one of our expert chefs, and afterwards they are able to sit down and enjoy the meal they have just created. Served with red & white wine.
8
Start:Jean Lafitte National Historical Park and Preserve
New Orleans, Louisiana·
4.5
(999) review
Nature reserve, consisting of several sections, preserves significant examples of the natural and cultural resources of the Mississippi Delta region.
9
Start:The Presbytere
New Orleans, Louisiana·
4.5
(999) review
The Presbytere was designed in 1791 to match the Cabildo, alongside St. Louis Cathedral in the French Quarter. It stands today as a beautiful reminder of both Louisiana's singular past and its vibrant present.The Presbytere, originally called Casa Curial or "Ecclesiastical House," was built on the site of the residence, or presbytere, of the Capuchin monks. The building was used for commercial purposes until 1834 when it became a courthouse. In 1911, it became part of the Louisiana State Museum. Two exhibitions are on display-"Living with Hurricanes: Katrina and Beyond" tells of rescue, rebuilding and renewal, and "Mardi Gras: It's Carnival Time in Louisiana" captures the fun and fantasy of the annual celebration.
10
Start:Palm Court Jazz Cafe
New Orleans, Louisiana·
4.5
(99) review
A stylish jazz spot in the French Quarter, which serves Cajun and Creole dishes.
11
Start:McWane Science Center
Birmingham, Alabama·
4.5
(963) review
Fun and learning never end at McWane Science Center, a nonprofit, hands-on museum and IMAX(R) Dome Theater. Four floors of interactive exhibits celebrate science and wonder - from an amazing collection of dinosaurs to innovative environmental showcases, imaginative early childhood playgrounds, and an awe-inspiring aquarium. The energy and excitement of discovery spring to life through an extensive lineup of science demonstrations performed daily by talented educators. The adventure intensifies in the IMAX(R) Dome Theater, where wide-eyed visitors experience the sights and sounds of breathtaking films on a 5-story-tall screen surrounded by 3 tons of high-intensity speakers.
12
Start:Statue of Liberty Replica
Birmingham, Alabama·
4.0
(97) review
Bronze replica measuring one-fifth the size of its sister statue located in New York City.
13
Start:River Gallery
Chattanooga, Tennessee·
4.5
(98) review
Craft and art collections.
14
Start:Chattanooga Zoo
Chattanooga, Tennessee·
4.0
(907) review
Imagine a zoo that's specially designed to bring the animals up close to you. Imagine a zoo where you have time to notice the subtleties of animal behavior, instead of being pushed along by an impatient crowd. Imagine an exciting and diverse zoo that's still easy to navigate with strollers...or little legs. That's the new Chattanooga Zoo!
15
Start:The Spice & Tea Exchange of Chattanooga
Chattanooga, Tennessee·
5.0
(92) review
Come In and Smell the Spices! The Spice & Tea Exchange® offers food lovers, chefs, and tea enthusiasts a unique shopping experience filled with culinary delights. Explore your inner chef and shop over 140 fine spices, 75+ hand-mixed seasoning blends, sugars, salts, loose-leaf teas, and accessories. Create your own gourmet gift, or choose from a variety of gift boxes and recipe samplers!
16
Start:Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
17
Start:Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
CHECKLIST
GPS device or app
Download Offline Map
Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
Camera or smartphone
Unlock Effortless Travel Planning
Create your dream trip in minutes by this prompt. Try now!
EXPLORE MORE
Discover Exciting Road Trip Inspirations
Houston to Dallas
237 miles
4h 13m
25 stops
MuseumsNightlifeSights & LandmarksConcerts & ShowsWater & Amusement Parks
Houston to Phoenix
1,185 miles
20h 0m
24 stops
NightlifeFun & GamesNature & ParksMuseumsSights & Landmarks
Houston to San Antonio
196 miles
3h 33m
17 stops
Sights & LandmarksSpas & WellnessNightlifeFun & GamesMuseums
Houston to San Diego
1,464 miles
24h 54m
21 stops
NightlifeFun & GamesNature & ParksMuseumsSights & Landmarks
Houston to Fort Worth
262 miles
4h 47m
27 stops
MuseumsSights & LandmarksConcerts & ShowsWater & Amusement ParksNature & Parks
Houston to Jacksonville
872 miles
15h 56m
27 stops
Traveler ResourcesNature & ParksMuseumsToursFun & Games
EXPLORE OTHER
Check Out Different Road Trip Options
Fort Collins to Rockford
959 miles
16h 51m
32 stops
ShoppingFun & GamesMuseumsNature & ParksWater & Amusement Parks
Birmingham to Leesburg
482 miles
9h 46m
14 stops
Sights & LandmarksWater & Amusement ParksOutdoor ActivitiesConcerts & ShowsFun & Games
Worcester to Yonkers
166 miles
3h 25m
39 stops
Concerts & ShowsFun & GamesShoppingToursNightlife
Leesburg to Rancho Cucamonga
2,438 miles
42h 41m
37 stops
Sights & LandmarksWater & Amusement ParksOutdoor ActivitiesConcerts & ShowsFun & Games
Kansas City to Mission Viejo
1,625 miles
28h 5m
23 stops
Outdoor ActivitiesMuseumsTraveler ResourcesNature & ParksSights & Landmarks
Bakersfield to Ocala
2,463 miles
44h 0m
36 stops
Fun & GamesOutdoor ActivitiesNature & ParksToursSights & Landmarks
FAQ
Frequently Asked Questions
What's the driving distance between Houston and Knoxville?
The distance is 923 miles
What's the travel time between Houston and Knoxville?
The driving time can vary depending on traffic conditions, but it is typically 16h 58m mins in normal traffic
What are some of the best cities to visit between Houston and Knoxville?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Knoxville?
There are plenty! Here are some stops you shouldn’t miss on your way to Knoxville
What’s the weather like in Knoxville?
The weather in Knoxville is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Knoxville in January
Weather in Knoxville in February
Weather in Knoxville in March
Weather in Knoxville in April
Weather in Knoxville in May
Weather in Knoxville in June
Weather in Knoxville in July
Weather in Knoxville in August
Weather in Knoxville in September
Weather in Knoxville in October
Weather in Knoxville in November
Weather in Knoxville in December
Interested in a detailed plan for your time in Knoxville?
Plan your dream Knoxville trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Knoxville
A 2-day itinerary in Knoxville
A 3-day itinerary in Knoxville
A 4-day itinerary in Knoxville
A 5-day itinerary in Knoxville
A 6-day itinerary in Knoxville
Where else can I travel to if I'm starting my trip in Houston?
We have a lot of great trip options for Houston! See the links below for all the itineraries we created for you