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By Huuk Team

Road trip from Fredericksburg to Knoxville

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Show more (3+)

ITINERARY

8h 22m431 miles18 stops
1
Woodlawn & Pope-Leighey House
9000 Richmond Hwy, Alexandria, VA 22309-1506
Woodlawn Estate and the Frank Lloyd Wright-designed Pope-Leighey House are two iconic architectural sites of the National Trust for Historic Preservation, located on the same property in historic Alexandria, Virginia, just outside Washington D.C. Our Federal Georgian Mansion, built in 1805 for Nelly Parke Custis Lewis and Lawrence Lewis and our Frank Lloyd Wright-designed Usonian House, built in 1940 and moved to our property in the 60's both sit in a beautiful landscape. Visitors are encouraged to explore the contrasting architectural and historical stories of these two masterpiece homes, set in glorious landscape. Our site is also home to the non-profit farm, Arcadia Center for Sustainable Food & Agriculture.
2
Grist Mill Park
4710 Mount Vernon Memorial Hwy, Alexandria, VA 22309-3228
3
Huntley Meadows Park
3701 Lockheed Blvd Telegraph Road and South Kings Highway Intersection, Alexandria, VA 22306-2060
4
River Farm
7931 E Boulevard Dr, Alexandria, VA 22308-1307
River Farm is the headquarters of the American Horticultural Society. Situated on 25 landscaped acres overlooking the Potomac river, it is an idyllic escape within the Washington, D.C. area. Enjoy walking in our gardens and four-acre Meadow. Bring kids to enjoy the Children's Garden. We are open year-round Monday-Friday 9 am - 5 pm. From April through September we are also open Saturday from 9 am - 1 pm.
5
Carvins Cove Natural Reserve
9644 Reservoir Rd, Roanoke, VA 24019-7916
6
St. Andrew's Roman Catholic Church
631 N Jefferson St, Roanoke, VA 24016-1401
7
Science Museum of Western Virginia & Hopkins Planetarium
1 Market Sq SE 4th Floor, Roanoke, VA 24011-1429
Fun for the whole family, the Science Museum of Western Virginia features a tropical butterfly garden filled with butterflies from around the world; fun and interactive exhibits exploring Healthy Bodies, Healthy Earth and How It Works; live animals and the popular "FROGS"; the Living River & Touch Tank; and amazing traveling exhibits such as "TUTANKHAMUN: Wonderful Things From The Pharaoh's Tomb," running June 14-Dec. 31, 2014.
8
Ladles & Linens Kitchen Shoppe
305 Market St SE, Roanoke, VA 24011-2105
9
Virginia Museum of Transportation
303 Norfolk Ave SW, Roanoke, VA 24016-3620
Antique automobiles and trucks, electric and deisel locomotives, and vintage steam, are all part of the nostalgic show at this historic freight station that doubles as a museum .
10
Green Ridge Recreation Center & Splash Valley Water Park
7415 Wood Haven Rd, Roanoke, VA 24019-1901
Designed with family fun in mind, Green Ridge offers two great attractions in one convenient location! The indoor center is open year round, featuring family friendly activities like swimming, interactive games, a gymnasium and fitness area. Splash Valley Water Park is an outdoor aquatics area open Memorial Day to Labor Day, featuring two 34-foot high slides, a sprayground and a current river. Daily admission is available to either facility.
11
A Few Old Goats Brewing
515 8th St Suite 228, Roanoke, VA 24016-3530
12
Iron Heart Winery
3742 Boone Furnace Rd, Allisonia, VA 24347-4001
13
Muse Knoxville
516 N Beaman St, Knoxville, TN 37914-4410
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
14
Knoxville Botanical Garden
2743 Wimpole Ave, Knoxville, TN 37914-5958
15
The Mill and Mine
227 W Depot Ave, Knoxville, TN 37917-7521
16
Krutch Park
504 Market St, Knoxville, TN 37902-2107
17
Peter Kern Library
407 Union Ave, Knoxville, TN 37902-2112
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
18
Cathedral of the Most Sacred Heart of Jesus
711 S Northshore Dr, Knoxville, TN 37919-7593
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OVERVIEW

Fredericksburg to Knoxville
1
Start:Woodlawn & Pope-Leighey House
Alexandria, Virginia·
4.5
(266) review
Woodlawn Estate and the Frank Lloyd Wright-designed Pope-Leighey House are two iconic architectural sites of the National Trust for Historic Preservation, located on the same property in historic Alexandria, Virginia, just outside Washington D.C. Our Federal Georgian Mansion, built in 1805 for Nelly Parke Custis Lewis and Lawrence Lewis and our Frank Lloyd Wright-designed Usonian House, built in 1940 and moved to our property in the 60's both sit in a beautiful landscape. Visitors are encouraged to explore the contrasting architectural and historical stories of these two masterpiece homes, set in glorious landscape. Our site is also home to the non-profit farm, Arcadia Center for Sustainable Food & Agriculture.
9000 Richmond Hwy, Alexandria, VA 22309-1506
2
Grist Mill Park
Alexandria, Virginia·
4.5
(28) review
4710 Mount Vernon Memorial Hwy, Alexandria, VA 22309-3228
3
Huntley Meadows Park
Alexandria, Virginia·
4.5
(244) review
3701 Lockheed Blvd Telegraph Road and South Kings Highway Intersection, Alexandria, VA 22306-2060
4
River Farm
Alexandria, Virginia·
4.5
(52) review
River Farm is the headquarters of the American Horticultural Society. Situated on 25 landscaped acres overlooking the Potomac river, it is an idyllic escape within the Washington, D.C. area. Enjoy walking in our gardens and four-acre Meadow. Bring kids to enjoy the Children's Garden. We are open year-round Monday-Friday 9 am - 5 pm. From April through September we are also open Saturday from 9 am - 1 pm.
7931 E Boulevard Dr, Alexandria, VA 22308-1307
5
Carvins Cove Natural Reserve
Roanoke, Virginia·
4.5
(95) review
9644 Reservoir Rd, Roanoke, VA 24019-7916
6
St. Andrew's Roman Catholic Church
Roanoke, Virginia·
4.5
(93) review
631 N Jefferson St, Roanoke, VA 24016-1401
7
Science Museum of Western Virginia & Hopkins Planetarium
Roanoke, Virginia·
4.0
(94) review
Fun for the whole family, the Science Museum of Western Virginia features a tropical butterfly garden filled with butterflies from around the world; fun and interactive exhibits exploring Healthy Bodies, Healthy Earth and How It Works; live animals and the popular "FROGS"; the Living River & Touch Tank; and amazing traveling exhibits such as "TUTANKHAMUN: Wonderful Things From The Pharaoh's Tomb," running June 14-Dec. 31, 2014.
1 Market Sq SE 4th Floor, Roanoke, VA 24011-1429
8
Ladles & Linens Kitchen Shoppe
Roanoke, Virginia·
5.0
(8) review
305 Market St SE, Roanoke, VA 24011-2105
9
Virginia Museum of Transportation
Roanoke, Virginia·
4.5
(715) review
Antique automobiles and trucks, electric and deisel locomotives, and vintage steam, are all part of the nostalgic show at this historic freight station that doubles as a museum .
303 Norfolk Ave SW, Roanoke, VA 24016-3620
10
Green Ridge Recreation Center & Splash Valley Water Park
Roanoke, Virginia·
4.0
(73) review
Designed with family fun in mind, Green Ridge offers two great attractions in one convenient location! The indoor center is open year round, featuring family friendly activities like swimming, interactive games, a gymnasium and fitness area. Splash Valley Water Park is an outdoor aquatics area open Memorial Day to Labor Day, featuring two 34-foot high slides, a sprayground and a current river. Daily admission is available to either facility.
7415 Wood Haven Rd, Roanoke, VA 24019-1901
11
A Few Old Goats Brewing
Roanoke, Virginia·
4.5
(9) review
515 8th St Suite 228, Roanoke, VA 24016-3530
12
Iron Heart Winery
Allisonia, Virginia·
4.0
(7) review
3742 Boone Furnace Rd, Allisonia, VA 24347-4001
13
Muse Knoxville
Knoxville, Tennessee·
4.0
(91) review
Muse Knoxville is a children’s Science, Technology, Engineering, Arts, & Math (STEAM) museum located in Chilhowee Park. Our programs in the museum, in schools across East Tennessee, & throughout Knoxville bring STEM, the arts, health & wellness, & emergent literacy to life in the minds of children. We inspire & empower ALL children through transformative learning experiences through a variety of hands-on and inquiry-based, exhibits and Outreach programs for children aged 6 mos. to 10 y/o. *Museum Play - Indoor educational learning & play spaces, a full-dome planetarium, outdoor learning spaces & a playground! *Field Trips - Bring your class, homeschool, daycare or youth group for a day of fun! *Parties/Events - Choose from a variety of packages to celebrate your special day with us. *Planetarium - We house East Tennessee's only public-access planetarium with shows that rotate every hour!
516 N Beaman St, Knoxville, TN 37914-4410
14
Knoxville Botanical Garden
Knoxville, Tennessee·
3.5
(97) review
2743 Wimpole Ave, Knoxville, TN 37914-5958
15
The Mill and Mine
Knoxville, Tennessee·
5.0
(9) review
227 W Depot Ave, Knoxville, TN 37917-7521
16
Krutch Park
Knoxville, Tennessee·
4.5
(90) review
504 Market St, Knoxville, TN 37902-2107
17
Peter Kern Library
Knoxville, Tennessee·
4.0
(99) review
Hidden inside the historic Kern Building, behind The Oliver Hotel lobby, is Knoxville’s one and only speakeasy, The Peter Kern Library. Once a well-kept secret, the bar is now a beloved institution. The dark wood, fireplace, rows of books, and cocktails named after literary characters create a warm and cozy atmosphere where time seems to stop.
407 Union Ave, Knoxville, TN 37902-2112
18
Cathedral of the Most Sacred Heart of Jesus
Knoxville, Tennessee·
4.5
(9) review
711 S Northshore Dr, Knoxville, TN 37919-7593

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FAQ
Frequently Asked Questions
What's the driving distance between Fredericksburg and Knoxville?
The distance is 431 miles
What's the travel time between Fredericksburg and Knoxville?
The driving time can vary depending on traffic conditions, but it is typically 8h 22m mins in normal traffic
What are some of the best cities to visit between Fredericksburg and Knoxville?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Knoxville?
There are plenty! Here are some stops you shouldn’t miss on your way to Knoxville
What’s the weather like in Knoxville?
The weather in Knoxville is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Knoxville in January
Weather in Knoxville in February
Weather in Knoxville in March
Weather in Knoxville in April
Weather in Knoxville in May
Weather in Knoxville in June
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Weather in Knoxville in August
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Weather in Knoxville in October
Weather in Knoxville in November
Weather in Knoxville in December
Interested in a detailed plan for your time in Knoxville?
Plan your dream Knoxville trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Knoxville
A 2-day itinerary in Knoxville
A 3-day itinerary in Knoxville
A 4-day itinerary in Knoxville
A 5-day itinerary in Knoxville
A 6-day itinerary in Knoxville
Where else can I travel to if I'm starting my trip in Fredericksburg?
We have a lot of great trip options for Fredericksburg! See the links below for all the itineraries we created for you