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By Huuk Team

Road trip from Buffalo to Winston-Salem

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ITINERARY

11h 43m606 miles16 stops
1
The Buffalo History Museum
1 Museum Ct, Buffalo, NY 14216-3160
2
Inniskillin Wines
1499 Line 3, Niagara-on-the-Lake, Ontario L0S 1J0 Canada
Many of those who appreciate and collect wine have discovered that a journey to the heart of wine country adds an indescribable dimension to the appreciation of the distinctiveness of each fine wine. In that spirit, Inniskillin invites you to fully experience our full VQA portfolio in Niagara-on-the-Lake. Experience firsthand the full range of our premium wines while enjoying spectacular sights, regional culinary specialties and outstanding hospitality in one of Canada's great natural treasures, the Niagara Peninsula. We look forward to toasting your arrival!
3
Erie Bayfront Convention Center
1 Sassafras Pier, Erie, PA 16507-2011
4
Presque Isle Downs & Casino
8199 Perry Hwy, Erie, PA 16509-6640
Presque Isle Downs & Casino is your best bet for gaming excitement! With over 1,500 of the hottest slots, you'll find a thrilling new game to spin every time you play. Prefer tables? You're in luck! Come try your hand at any of our over 30 thrilling table games. Like to bet on sports? Get in the game at our TwinSpires Sportsbook! With convenient sports betting kiosks, wagering is quick and easy so you'll never miss a minute of the action. Plus, catch seasonal live thoroughbred horse racing at our track! While you're here be sure to sign up for our Players Club. All new members get up to $2,500 free slot play or $25 in guaranteed match play right out of the gate! It's fast and free to join. Every time you play with your Players Club card you'll earn valuable reward points that qualify you to enjoy members-only promotions, perks, exclusive offers and much more! Presque Isle Downs & Casino is located in Erie, PA, just off of I-90 at Exit 27. Gambling Problem? Call 1-800 GAMBLER.
5
Allegheny Cemetery
4734 Butler St, Pittsburgh, PA 15201-2951
Instituted in 1844, this 300-acre cemetery is the final resting place of such notables as Lillian Russell, Stephen Foster and General John Neville.
6
Cathedral of Learning
4200 5th Ave., Pittsburgh, PA 15260
7
Pittsburgh Water Steps
North Shore Riverfront Park, Pittsburgh, PA 15212
8
Point State Park
601 Commonwealth Pl Bldg A, Pittsburgh, PA 15222
Serving as a key strategic spot during the French and Indian War, this National Historic Landmark and park offer stunning views of the city and a variety of outdoor recreation.
9
Iron Heart Winery
3742 Boone Furnace Rd, Allisonia, VA 24347-4001
10
Grand 18-Winston-Salem
5601 University Pkwy, Winston Salem, NC 27105-1313
11
Lam Museum of Anthropology, Wake Forest University
Palmer Hall, Carroll Weathers Drive, Winston Salem, NC 27109
Discover North Carolina's only museum dedicated to the study of global cultures. Explore stories of humanity, from ancient archaeological sites to the celebrations and struggles of today. Learn about peoples around the world through their everyday and ceremonial objects, and visual arts. Changing exhibits highlight the Museum's collections of nearly 30,000 archaeological and ethnographic artifacts from more than 350 cultures and 90 countries. Admission is free.
12
European Touch
116 Reynolda Vlg, Winston Salem, NC 27106-5123
13
Reynolda House Museum of American Art
2250 Reynolda Rd, Winston Salem, NC 27106-5117
Nestled within 180 acres adjacent to Wake Forest University, Reynolda is the perfect place to escape and discover art, nature, history, and so much more. View Reynolda’s world-renowned American art collection and curated exhibitions on display throughout the interiors of Katharine and R.J. Reynolds’s 1917 bungalow and in the Babcock Gallery. Plus, learn about the Reynolds family, Katharine’s vision, and the history of the estate. After touring the Museum, embrace the outdoors in the Gardens and grounds, which are always free and open to the public year-round from sunrise to sunset. Do flowers make you hungry? Make your way to Reynolda Village to shop and dine.
14
Salem Lake
1001 Salem Lake Rd, Winston Salem, NC 27107-1571
15
Recreation Billiards
412 W 4th St, Winston Salem, NC 27101-2805
16
JDL Fast Track
2505 Empire Dr, Winston Salem, NC 27103-6709
Customize this Trip

OVERVIEW

1
Start:The Buffalo History Museum
Buffalo, Erie County, New York·
4.0
(97) review
1 Museum Ct, Buffalo, NY 14216-3160
2
Inniskillin Wines
Niagara-on-the-Lake, Ontario·
4.5
(969) review
Many of those who appreciate and collect wine have discovered that a journey to the heart of wine country adds an indescribable dimension to the appreciation of the distinctiveness of each fine wine. In that spirit, Inniskillin invites you to fully experience our full VQA portfolio in Niagara-on-the-Lake. Experience firsthand the full range of our premium wines while enjoying spectacular sights, regional culinary specialties and outstanding hospitality in one of Canada's great natural treasures, the Niagara Peninsula. We look forward to toasting your arrival!
1499 Line 3, Niagara-on-the-Lake, Ontario L0S 1J0 Canada
3
Erie Bayfront Convention Center
Erie, Pennsylvania·
4.5
(97) review
1 Sassafras Pier, Erie, PA 16507-2011
4
Presque Isle Downs & Casino
Erie, Pennsylvania·
3.5
(981) review
Presque Isle Downs & Casino is your best bet for gaming excitement! With over 1,500 of the hottest slots, you'll find a thrilling new game to spin every time you play. Prefer tables? You're in luck! Come try your hand at any of our over 30 thrilling table games. Like to bet on sports? Get in the game at our TwinSpires Sportsbook! With convenient sports betting kiosks, wagering is quick and easy so you'll never miss a minute of the action. Plus, catch seasonal live thoroughbred horse racing at our track! While you're here be sure to sign up for our Players Club. All new members get up to $2,500 free slot play or $25 in guaranteed match play right out of the gate! It's fast and free to join. Every time you play with your Players Club card you'll earn valuable reward points that qualify you to enjoy members-only promotions, perks, exclusive offers and much more! Presque Isle Downs & Casino is located in Erie, PA, just off of I-90 at Exit 27. Gambling Problem? Call 1-800 GAMBLER.
8199 Perry Hwy, Erie, PA 16509-6640
5
Allegheny Cemetery
Pittsburgh, Pennsylvania·
4.5
(94) review
Instituted in 1844, this 300-acre cemetery is the final resting place of such notables as Lillian Russell, Stephen Foster and General John Neville.
4734 Butler St, Pittsburgh, PA 15201-2951
6
Cathedral of Learning
Pittsburgh, Pennsylvania·
4.5
(979) review
4200 5th Ave., Pittsburgh, PA 15260
7
Pittsburgh Water Steps
Pittsburgh, Pennsylvania·
4.5
(94) review
North Shore Riverfront Park, Pittsburgh, PA 15212
8
Point State Park
Pittsburgh, Pennsylvania·
4.5
(951) review
Serving as a key strategic spot during the French and Indian War, this National Historic Landmark and park offer stunning views of the city and a variety of outdoor recreation.
601 Commonwealth Pl Bldg A, Pittsburgh, PA 15222
9
Iron Heart Winery
Allisonia, Virginia·
4.0
(7) review
3742 Boone Furnace Rd, Allisonia, VA 24347-4001
10
Grand 18-Winston-Salem
Winston Salem, North Carolina·
4.0
(72) review
5601 University Pkwy, Winston Salem, NC 27105-1313
11
Lam Museum of Anthropology, Wake Forest University
Winston Salem, North Carolina·
4.0
(9) review
Discover North Carolina's only museum dedicated to the study of global cultures. Explore stories of humanity, from ancient archaeological sites to the celebrations and struggles of today. Learn about peoples around the world through their everyday and ceremonial objects, and visual arts. Changing exhibits highlight the Museum's collections of nearly 30,000 archaeological and ethnographic artifacts from more than 350 cultures and 90 countries. Admission is free.
Palmer Hall, Carroll Weathers Drive, Winston Salem, NC 27109
12
European Touch
Winston Salem, North Carolina·
5.0
(5) review
116 Reynolda Vlg, Winston Salem, NC 27106-5123
13
Reynolda House Museum of American Art
Winston Salem, North Carolina·
4.5
(659) review
Nestled within 180 acres adjacent to Wake Forest University, Reynolda is the perfect place to escape and discover art, nature, history, and so much more. View Reynolda’s world-renowned American art collection and curated exhibitions on display throughout the interiors of Katharine and R.J. Reynolds’s 1917 bungalow and in the Babcock Gallery. Plus, learn about the Reynolds family, Katharine’s vision, and the history of the estate. After touring the Museum, embrace the outdoors in the Gardens and grounds, which are always free and open to the public year-round from sunrise to sunset. Do flowers make you hungry? Make your way to Reynolda Village to shop and dine.
2250 Reynolda Rd, Winston Salem, NC 27106-5117
14
Salem Lake
Winston Salem, North Carolina·
4.5
(97) review
1001 Salem Lake Rd, Winston Salem, NC 27107-1571
15
Recreation Billiards
Winston Salem, North Carolina·
4.0
(9) review
412 W 4th St, Winston Salem, NC 27101-2805
16
JDL Fast Track
Winston Salem, North Carolina·
4.0
(9) review
2505 Empire Dr, Winston Salem, NC 27103-6709

CHECKLIST

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Water bottles and snacks
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Travel pillow and blanket
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Hand sanitizer and wet wipes
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Driver’s license and vehicle registration
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Cash and cards
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FAQ
Frequently Asked Questions
What's the driving distance between Buffalo and Winston-Salem?
The distance is 606 miles
What's the travel time between Buffalo and Winston-Salem?
The driving time can vary depending on traffic conditions, but it is typically 11h 43m mins in normal traffic
What are some of the best cities to visit between Buffalo and Winston-Salem?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Winston-Salem?
There are plenty! Here are some stops you shouldn’t miss on your way to Winston-Salem
What’s the weather like in Winston-Salem?
The weather in Winston-Salem is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Winston-Salem in January
Weather in Winston-Salem in February
Weather in Winston-Salem in March
Weather in Winston-Salem in April
Weather in Winston-Salem in May
Weather in Winston-Salem in June
Weather in Winston-Salem in July
Weather in Winston-Salem in August
Weather in Winston-Salem in September
Weather in Winston-Salem in October
Weather in Winston-Salem in November
Weather in Winston-Salem in December
Interested in a detailed plan for your time in Winston-Salem?
Plan your dream Winston-Salem trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Winston-Salem
A 2-day itinerary in Winston-Salem
A 3-day itinerary in Winston-Salem
A 4-day itinerary in Winston-Salem
A 5-day itinerary in Winston-Salem
A 6-day itinerary in Winston-Salem
Where else can I travel to if I'm starting my trip in Buffalo?
We have a lot of great trip options for Buffalo! See the links below for all the itineraries we created for you