Road trip from Buffalo to Mesa
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All Category
Museums
Concerts & Shows
Outdoor Activities
Fun & Games
Food & Drink
Spas & Wellness
Nature & Parks
Nightlife
Sights & Landmarks
Casinos & Gambling
Boat Tours & Water Sports
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ITINERARY
39h 46m2,187 miles24 stops
1
The Buffalo History Museum
2
Inniskillin Wines
Many of those who appreciate and collect wine have discovered that a journey to the heart of wine country adds an indescribable dimension to the appreciation of the distinctiveness of each fine wine. In that spirit, Inniskillin invites you to fully experience our full VQA portfolio in Niagara-on-the-Lake. Experience firsthand the full range of our premium wines while enjoying spectacular sights, regional culinary specialties and outstanding hospitality in one of Canada's great natural treasures, the Niagara Peninsula. We look forward to toasting your arrival!
3
Presque Isle Downs & Casino
Presque Isle Downs & Casino is your best bet for gaming excitement! With over 1,500 of the hottest slots, you'll find a thrilling new game to spin every time you play. Prefer tables? You're in luck! Come try your hand at any of our over 30 thrilling table games. Like to bet on sports? Get in the game at our TwinSpires Sportsbook! With convenient sports betting kiosks, wagering is quick and easy so you'll never miss a minute of the action. Plus, catch seasonal live thoroughbred horse racing at our track! While you're here be sure to sign up for our Players Club. All new members get up to $2,500 free slot play or $25 in guaranteed match play right out of the gate! It's fast and free to join. Every time you play with your Players Club card you'll earn valuable reward points that qualify you to enjoy members-only promotions, perks, exclusive offers and much more! Presque Isle Downs & Casino is located in Erie, PA, just off of I-90 at Exit 27. Gambling Problem? Call 1-800 GAMBLER.
4
Rock & Roll Hall of Fame
Headquartered in a boldly designed building on Lake Erie's shore, The Rock and Roll Hall of Fame is a 150,000-square-foot museum featuring ever-changing exhibits documenting the history of rock and roll, from Elvis to our days. You’ll see hundreds of original artifacts, from Jimi Hendrix outfits to The Beatles’ handwritten lyrics. Experience the excitement of a Rock Hall induction night at the Power of Rock Experience or have your very own jam session at the Garage. You can also watch a concert while you're here, so check out the Rock Hall’s schedule and plan ahead. – Tripadvisor
5
Federal Reserve Bank of Cleveland: Education and Learning Center
Ever wonder how money works or what the Federal Reserve Bank of Cleveland does as part of the central bank of the US? Visit our Education and Learning Center featuring more than 25 fun, hands-on exhibits that answer these questions and more! We have interactive games, visual exhibits, creative stations, and illuminating films that explain everything about money you can think of, from how we use it, to why it looks the way it looks. Come see our historic lobby, take pictures with our money tree, trade coconuts on Barter Island, identify counterfeit bills, and even make your own money! All this in the heart of Cleveland, just steps away from downtown attractions. Admission is free and photos are welcome.
6
Lock 3
7
Ohio Stadium
8
Kelton House Museum & Garden
Experience urban life and the decorative arts, as they existed in the second half of the 19th century, through the collection of the Sophia and Fernando Cortez Kelton family. Learn about the Underground Railroad and the people that bring the history to life.
9
Galloway Creek Greenway
10
Springfield Art Museum
11
Route 66 Car Museum
12
BOK Center
13
Vintage Sewing Center And Museum
14
Topgolf Oklahoma City
Topgolf is the emerging global leader in golf entertainment. Players hit golf balls containing computer microchips that track each shot’s accuracy and distance while also awarding points for hitting targets on the outfield. Topgolf offers an upscale, laid-back experience that features climate-controlled hitting bays and an impressive food and beverage menu crafted by our executive chef.
15
Brickopolis
16
Myriad Botanical Gardens
Myriad Botanical Gardens is one of Oklahoma City’s most beloved public spaces, offering its visitors a 15 acre natural escape in the heart of downtown. A half-acre children’s garden, an off-leash dog park, splash fountains, and paths for walking and jogging provide guests young and old with a place to seek solitude with nature, or seek community and the company of others. The Gardens offers a variety of horticultural education programs for adults and children. The centerpiece attraction of the Gardens is the Inasmuch Foundation Crystal Bridge Conservatory. Its unique design has earned attention and praise in the architectural community. It is 224 feet long, 70 feet in diameter, and is covered by 3,028 sections of translucent, double-layered acrylic panels. After an 18-month, $11 million renovation, it reopened to the public on November 18, 2022.
17
Hinkle Fun Center
Hinkle Family Fun Center is Albuquerque's Premier Family Entertainment Destination located in sunny New Mexico. Hinkle Family Fun Center features two scenic 18 hole Miniature Golf Courses, a 1/8 mile twisting Go Kart Track, Rock Climbing, two Game Rooms and Prize Centers with over 150 redemption and arcade games, Bumper Boats, Bungee Jump Trampoline, a 4500 square foot black light themed Lazer Tag arena, XD Dark Ride, Lazer Frenzy, Bumper Cars, Light Space, Birthday Parties, Group Events and Cody’s Cafe too! Celebrating 25 years of making memories that matter!
18
La Cumbre Brewing Company
19
Betty's Bath and Day Spa
Betty's features two outdoor hot tubs and saunas, massages, facials, restorative spa treatments, lounge and relaxation areas in a xeriscaped garden setting, and a specialty boutique with natural and scintillating bath & body products as well as sassy and stylish affordable accessories.
20
Paseo Vista Recreation Area
21
Wild West Horse Adventures
Experience the Sonoran Desert the way it was intended, on horseback. We offer private trail rides in the Sonoran Preserve. They are maintained to provide the most exceptional experience that you'll remember for a lifetime. Let's hit the trails!
22
Troon North Golf Club Monument Course
The Monument Course, which opened in 1990, was conceived by legendary golfer Tom Weiskopf and Architect Jay Morrish. In 2007, the course underwent a major renovation project, led by Tom Weiskopf. An entirely new playing experience was created by exchanging its front nine holes with the front nine of its sibling course, the Pinnacle Course, and changing the sequence in which the holes are played. Hallmarks of the course include balance, variety and immaculate course conditions.
23
Medieval Times Dinner & Tournament
24
Arizona Science Center
Located in the heart of Downtown Phoenix, Arizona Science Center has been a hub for science and discovery for the community and visitors. Featuring more than 300 hands-on exhibits, live demonstrations, a range of interactive online science content, the state-of-the-art Dorrance Planetarium, and the five-story Irene P. Flinn Giant Screen Theater– Arizona Science Center offers programs for all ages. For further details, please visit azscience.org.
Customize this Trip
OVERVIEW
1
Start:The Buffalo History Museum
Buffalo, Erie County, New York·
4.0
(97) review
1 Museum Ct, Buffalo, NY 14216-3160
2
Start:Inniskillin Wines
Niagara-on-the-Lake, Ontario·
4.5
(969) review
Many of those who appreciate and collect wine have discovered that a journey to the heart of wine country adds an indescribable dimension to the appreciation of the distinctiveness of each fine wine. In that spirit, Inniskillin invites you to fully experience our full VQA portfolio in Niagara-on-the-Lake. Experience firsthand the full range of our premium wines while enjoying spectacular sights, regional culinary specialties and outstanding hospitality in one of Canada's great natural treasures, the Niagara Peninsula. We look forward to toasting your arrival!
3
Start:Presque Isle Downs & Casino
Erie, Pennsylvania·
3.5
(981) review
Presque Isle Downs & Casino is your best bet for gaming excitement! With over 1,500 of the hottest slots, you'll find a thrilling new game to spin every time you play. Prefer tables? You're in luck! Come try your hand at any of our over 30 thrilling table games. Like to bet on sports? Get in the game at our TwinSpires Sportsbook! With convenient sports betting kiosks, wagering is quick and easy so you'll never miss a minute of the action. Plus, catch seasonal live thoroughbred horse racing at our track! While you're here be sure to sign up for our Players Club. All new members get up to $2,500 free slot play or $25 in guaranteed match play right out of the gate! It's fast and free to join. Every time you play with your Players Club card you'll earn valuable reward points that qualify you to enjoy members-only promotions, perks, exclusive offers and much more! Presque Isle Downs & Casino is located in Erie, PA, just off of I-90 at Exit 27. Gambling Problem? Call 1-800 GAMBLER.
4
Start:Rock & Roll Hall of Fame
Cleveland, Ohio·
4.5
(9964) review
Headquartered in a boldly designed building on Lake Erie's shore, The Rock and Roll Hall of Fame is a 150,000-square-foot museum featuring ever-changing exhibits documenting the history of rock and roll, from Elvis to our days. You’ll see hundreds of original artifacts, from Jimi Hendrix outfits to The Beatles’ handwritten lyrics. Experience the excitement of a Rock Hall induction night at the Power of Rock Experience or have your very own jam session at the Garage. You can also watch a concert while you're here, so check out the Rock Hall’s schedule and plan ahead. – Tripadvisor
5
Start:Federal Reserve Bank of Cleveland: Education and Learning Center
Cleveland, Ohio·
4.5
(95) review
Ever wonder how money works or what the Federal Reserve Bank of Cleveland does as part of the central bank of the US? Visit our Education and Learning Center featuring more than 25 fun, hands-on exhibits that answer these questions and more! We have interactive games, visual exhibits, creative stations, and illuminating films that explain everything about money you can think of, from how we use it, to why it looks the way it looks. Come see our historic lobby, take pictures with our money tree, trade coconuts on Barter Island, identify counterfeit bills, and even make your own money! All this in the heart of Cleveland, just steps away from downtown attractions. Admission is free and photos are welcome.
6
Start:Lock 3
Akron, Ohio·
4.5
(98) review
200 S Main St, Akron, OH 44308-1315
7
Start:Ohio Stadium
Columbus, Ohio·
4.5
(979) review
411 Woody Hayes Dr,, Columbus, OH 43210-1104
8
Start:Kelton House Museum & Garden
Columbus, Ohio·
4.5
(96) review
Experience urban life and the decorative arts, as they existed in the second half of the 19th century, through the collection of the Sophia and Fernando Cortez Kelton family. Learn about the Underground Railroad and the people that bring the history to life.
9
Start:Galloway Creek Greenway
Springfield, Missouri·
5.0
(9) review
2120 S Ventura Ave Pershing Middle School, Springfield, MO 65804-2718
10
Start:Springfield Art Museum
Springfield, Missouri·
4.5
(99) review
1111 E Brookside Dr, Springfield, MO 65807-1899
11
Start:Route 66 Car Museum
Springfield, Missouri·
4.5
(95) review
1634 W College St, Springfield, MO 65806-1614
12
Start:BOK Center
Tulsa, Oklahoma·
4.5
(907) review
200 S Denver Ave, Tulsa, OK 74103-5019
13
Start:Vintage Sewing Center And Museum
Tulsa, Oklahoma·
5.0
(97) review
5528 S Peoria Ave, Tulsa, OK 74105-6822
14
Start:Topgolf Oklahoma City
Oklahoma City, Oklahoma·
4.5
(92) review
Topgolf is the emerging global leader in golf entertainment. Players hit golf balls containing computer microchips that track each shot’s accuracy and distance while also awarding points for hitting targets on the outfield. Topgolf offers an upscale, laid-back experience that features climate-controlled hitting bays and an impressive food and beverage menu crafted by our executive chef.
15
Start:Brickopolis
Oklahoma City, Oklahoma·
4.0
(96) review
101 S Mickey Mantle Dr, Oklahoma City, OK 73104-2480
16
Start:Myriad Botanical Gardens
Oklahoma City, Oklahoma·
4.5
(979) review
Myriad Botanical Gardens is one of Oklahoma City’s most beloved public spaces, offering its visitors a 15 acre natural escape in the heart of downtown. A half-acre children’s garden, an off-leash dog park, splash fountains, and paths for walking and jogging provide guests young and old with a place to seek solitude with nature, or seek community and the company of others. The Gardens offers a variety of horticultural education programs for adults and children. The centerpiece attraction of the Gardens is the Inasmuch Foundation Crystal Bridge Conservatory. Its unique design has earned attention and praise in the architectural community. It is 224 feet long, 70 feet in diameter, and is covered by 3,028 sections of translucent, double-layered acrylic panels. After an 18-month, $11 million renovation, it reopened to the public on November 18, 2022.
17
Start:Hinkle Fun Center
Albuquerque, New Mexico·
4.0
(95) review
Hinkle Family Fun Center is Albuquerque's Premier Family Entertainment Destination located in sunny New Mexico. Hinkle Family Fun Center features two scenic 18 hole Miniature Golf Courses, a 1/8 mile twisting Go Kart Track, Rock Climbing, two Game Rooms and Prize Centers with over 150 redemption and arcade games, Bumper Boats, Bungee Jump Trampoline, a 4500 square foot black light themed Lazer Tag arena, XD Dark Ride, Lazer Frenzy, Bumper Cars, Light Space, Birthday Parties, Group Events and Cody’s Cafe too! Celebrating 25 years of making memories that matter!
18
Start:La Cumbre Brewing Company
Albuquerque, New Mexico·
4.5
(92) review
3313 Girard Blvd NE, Albuquerque, NM 87107-1930
19
Start:Betty's Bath and Day Spa
Albuquerque, New Mexico·
4.5
(98) review
Betty's features two outdoor hot tubs and saunas, massages, facials, restorative spa treatments, lounge and relaxation areas in a xeriscaped garden setting, and a specialty boutique with natural and scintillating bath & body products as well as sassy and stylish affordable accessories.
20
Start:Paseo Vista Recreation Area
Chandler, Arizona·
5.0
(1) review
3850 S Mcqueen Rd, Chandler, AZ 85286
21
Start:Wild West Horse Adventures
Scottsdale, Arizona·
5.0
(97) review
Experience the Sonoran Desert the way it was intended, on horseback. We offer private trail rides in the Sonoran Preserve. They are maintained to provide the most exceptional experience that you'll remember for a lifetime. Let's hit the trails!
22
Start:Troon North Golf Club Monument Course
Scottsdale, Arizona·
4.5
(96) review
The Monument Course, which opened in 1990, was conceived by legendary golfer Tom Weiskopf and Architect Jay Morrish. In 2007, the course underwent a major renovation project, led by Tom Weiskopf. An entirely new playing experience was created by exchanging its front nine holes with the front nine of its sibling course, the Pinnacle Course, and changing the sequence in which the holes are played. Hallmarks of the course include balance, variety and immaculate course conditions.
23
Start:Medieval Times Dinner & Tournament
Scottsdale, Arizona·
4.0
(95) review
9051 East Via De Ventura, Scottsdale, AZ 85258
24
Start:Arizona Science Center
Phoenix, Arizona·
4.0
(967) review
Located in the heart of Downtown Phoenix, Arizona Science Center has been a hub for science and discovery for the community and visitors. Featuring more than 300 hands-on exhibits, live demonstrations, a range of interactive online science content, the state-of-the-art Dorrance Planetarium, and the five-story Irene P. Flinn Giant Screen Theater– Arizona Science Center offers programs for all ages. For further details, please visit azscience.org.
CHECKLIST
GPS device or app
Download Offline Map
Car charger and portable battery
Water bottles and snacks
Travel pillow and blanket
Sunglasses and sunscreen
First-aid kit
Trash bags
Hand sanitizer and wet wipes
Driver’s license and vehicle registration
Cash and cards
Camera or smartphone
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FAQ
Frequently Asked Questions
What's the driving distance between Buffalo and Mesa?
The distance is 2,187 miles
What's the travel time between Buffalo and Mesa?
The driving time can vary depending on traffic conditions, but it is typically 39h 46m mins in normal traffic
What are some of the best cities to visit between Buffalo and Mesa?
Some popular stops include
Are there any cool sights or attractions I shouldn't miss on my drive to Mesa?
There are plenty! Here are some stops you shouldn’t miss on your way to Mesa
What’s the weather like in Mesa?
The weather in Mesa is generally mild year-round, with warm, dry summers and cool, wet winters. See the links below for more information
Weather in Mesa in January
Weather in Mesa in February
Weather in Mesa in March
Weather in Mesa in April
Weather in Mesa in May
Weather in Mesa in June
Weather in Mesa in July
Weather in Mesa in August
Weather in Mesa in September
Weather in Mesa in October
Weather in Mesa in November
Weather in Mesa in December
Interested in a detailed plan for your time in Mesa?
Plan your dream Mesa trip with our daily itineraries featuring must-see attractions! See them here!
A 1-day itinerary in Mesa
A 2-day itinerary in Mesa
A 3-day itinerary in Mesa
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A 6-day itinerary in Mesa
Where else can I travel to if I'm starting my trip in Buffalo?
We have a lot of great trip options for Buffalo! See the links below for all the itineraries we created for you