Av. Paseo de la Reforma s/n, Bosque de Chapultepec I Secc, Miguel Hidalgo, Mexico City 11560 Mexico

Considered one of the world's most comprehensive natural history museums, this famous institution houses four square kilometers of exhibits in 23 exhibition halls.

Avenida Juarez y Eje Central s/n Centro Histórico, Mexico City 06050 Mexico

This historic white marble building serves as both the city's top performance hall and an art museum.

Bosque de Chapultepec I Secc, Mexico City 11100 Mexico

Learn about Mexico's fascinating history at Chapultepec Castle, a grand 18th-century palace atop a hill in Mexico City. The palace houses the National Museum of History, which showcases impressive murals and stunning stained glass galleries. You can also take a leisurely stroll through the castle's manicured gardens and enjoy the panoramic views of downtown. Make sure to set aside enough time to relax and enjoy the sprawling Chapultepec Park nearby, too. Take a guided tour to learn about the building's rich history, and consider visiting on a tour that also includes the nearby National Museum of Anthropology. Get there early for fewer crowds. – Tripadvisor

Calle Londres 247 Col. Del Carmen, Mexico City 04100 Mexico

The birthplace and lifelong home of Frida Kahlo is now a popular museum dedicated to her work and life. Nicknamed the Casa Azul for its bright blue exterior, the museum will take you through the beautifully decorated rooms and the quaint family garden, as you learn about the incredible influence of Frida Kahlo and her husband Diego Rivera. Catch a great glimpse into the life of Mexico's most famous artist through the impressive display of documents, clothes, and artwork. Get there early or pre-book your tickets online to avoid the lines. You can also explore the museum as part of a tour of Mexico City that often includes other sights like Xochimilco and Coyoacan. – Tripadvisor

Parque Centenario, Mexico City 04000 Mexico

Five centuries’ worth of architecture and Mexican culture are embedded in this district’s plazas and narrow cobbled streets. Start your tour of Coyoacan at the lively Jardin Centenario park which is surrounded by inviting cafes and townhouses. Then, set off to visit the Frida Kahlo Museum that is dedicated to the life and works of the Mexican artist herself. On the way there, pop by the artisans market to hunt for handmade keepsakes and visit the Coyoacan Market for fresh tostadas and gorditas. For a full experience, take a guided tour around Coyoacan, which includes a visit to the floating gardens of neighboring Xochimilco. – Tripadvisor

Fray Juan de Zumarraga No. 2 Villa Gustavo A. Madero, Mexico City 07050 Mexico

This famous church, located on the site where an Indian claimed to have seen the Virgin of Guadalupe in 1531, contains an image of her that is the most famous religious icon in all of Mexico.

Paseos de la Reforma No. 42, Mexico City Mexico

Mexico City's main street runs through an upscale residential neighborhood as well as the city's historic district.

Calle Plaza de La Constitucion S/N Centro Histórico de la Cdad. de México, Centro, Mexico City 06000 Mexico

Zocalo, or Plaza de la Constitucion, is one of Mexico City's most popular spots that dates back to the Aztec era. It's a large and historic public plaza that never sleeps, always buzzing with traditional Aztec dancers and performers, cultural events, and even political demonstrations. The square is surrounded by beautiful architecture and landmarks, such as Palacio Bellas Artes and the Templo Mayor, making it a great starting point to explore the city. Be sure to join a city walking tour to learn more about the history and culture of Zocalo. Visit in the morning or late afternoon for fewer crowds. – Tripadvisor

Calle Plaza de La Constitucion S/N Centro Histórico de la Cdad, Mexico City 06000 Mexico

One of the largest churches in Latin America, this famous cathedral dominates the Zócalo.

Seminario 8 Centro Histórico, Mexico City 06060 Mexico

The ruins of the temple the Aztecs believed to be center of the universe.

Blvd Miguel de Cervantes Saavedra 303 Col Ampliacion Granada, Miguel Hidalgo, Mexico City 11529 Mexico

This museum explores the role of art and culture in human life and includes art by such luminaries as the French sculptor Rodin.

Avenida Juarez 66, Mexico City 06000 Mexico

The designated location of many of Mexico's older colonial structures.

P.za De La Constitucion S/N, Centro Historico De La Cdad. De Mexico, Mexico City 06066 Mexico

This historic building was once occupied by Hernán Cortés, the Spanish explorer who conquered the Aztecs, and includes a famous panoramic mural of Mexican history by Diego Rivera.

Miguel Hidalgo, Mexico City Mexico

This 1,600-acre bucolic park has enough activities to fill days at a time and is particularly popular among families with children.

Calle Tacuba 1, Mexico City 06000 Mexico